Narrative review of closed loop automated oxygen systems

Stewart, Lyndsey; MacVicar, Sonya

Abstract

Preterm infants frequently require respiratory support with supplemental oxygen but excess and fluctuation of oxygen levels can have adverse effects. Oxygen saturation levels are maintained within narrow target ranges as a manual titration process. Closed loop automated oxygen systems hypothesis that automatic titration of inspired oxygen will reduce time spent out of desired oxygen target range compared with current manual control.

Aims
comparison of automated versus manual oxygen control for preterm neonates undergoing non-invasive ventilation plus supplemental oxygen.

Methods
Four electronic databases (CINAHL, Cochrane Library, Medline and PubMed) were searched with narrative review of findings.

Results
Four studies were included and all reported neonates spent more time in the oxygen target range with automated versus manual control with a wide variation in improvement from 8.8% to 30%.

Conclusions
Automated oxygen systems with non-invasive respiratory modalities can minimise time spent out with oxygen target range. Long term impact of automated control on incidence of oxidative stress injury remains undetermined.

Citation

Stewart, L., & MacVicar, S. (2023). Narrative review of closed loop automated oxygen systems. Journal of Neonatal Nursing, 29(2), 229-234. https://doi.org/10.1016/j.jnn.2022.05.005

• Journal Article Type: Article
• Acceptance Date: May 3, 2022
• Online Publication Date: May 11, 2022
• Publication Date: 2023-04
• Deposit Date: May 16, 2022
• Publicly Available Date: May 16, 2022
• Journal: Journal of Neonatal Nursing
• Print ISSN: 1355-1841
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 29
• Issue: 2
• Pages: 229-234
• DOI: https://doi.org/10.1016/j.jnn.2022.05.005
• Keywords: Narrative review, Closed loop automated oxygen system, CLAOS’ prematurity neonate, Non-invasive respiratory support, Supplementary oxygen, Oxygen saturation
• Public URL: http://researchrepository.napier.ac.uk/Output/2870427