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Air Pollution and Chronic Kidney Disease Risk in Oil and Gas- Situated Communities: A Systematic Review and Meta-Analysis

Okoye, Ogochukwu Chinedum; Carnegie, Elaine; Mora, Luca


Ogochukwu Chinedum Okoye


Objective: This systematic review and meta-analysis aimed at synthesising epidemiological data on the association between long-term air pollution and kidney-related outcomes in oil and natural gas (ONG) situated communities.

Methods: We synthesised studies using the PRISMA 2020 guideline. We searched databases including Medline, Cochrane Library, CIHANL, CAB Abstracts, Greenlife, African Journal Online, Google Scholar and Web of Science, from inception to April 2021. Heterogeneity across studies and publication bias were assessed.

Results: Twenty-five studies were systematically reviewed but only 14 were included in the meta-analysis and categorised based on the outcome studied. Residents of exposed communities have increased risk for Chronic Kidney Disease (CKD) (OR = 1.70, 95% CI 1.44–2.01), lower eGFR (OR = 0.55, 95% CI 0.48–0.67) and higher serum creatinine (OR = 1.39, 95% CI 1.06–1.82) compared to less exposed or unexposed populations. The risks for hypertension and kidney cancer between the two populations were not significantly different.

Conclusion: We report an increased risk for CKD and kidney dysfunction in populations residing near petrochemical plants, although from a limited number of studies. The scientific community needs to explore this environment and non-communicable disease relationship, particularly in vulnerable populations.

Journal Article Type Review
Acceptance Date Mar 15, 2022
Online Publication Date Apr 11, 2022
Publication Date 2022
Deposit Date Apr 27, 2022
Publicly Available Date Apr 27, 2022
Journal International Journal of Public Health
Print ISSN 1661-8556
Publisher Springer
Peer Reviewed Peer Reviewed
Volume 67
Article Number 1604522
Keywords kidney disease, systematic review, air pollution, meta-analysis, petrochemical plants, hypertension, oil and natural gas
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