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Trust, inflammatory biomarkers and adversity: a novel investigation and clinical implications

Chouliara, Zo�; Barlow, Peter G.


Zo� Chouliara


Survivors of adversity and trauma experience high levels of distress, interpersonal challenges and poor physical health. We investigated the role of trust in trauma-related psychological and physiological responses. Serum concentrations of C-reactive protein, cortisol, tumour necrosis factor-alpha and interleukin-8 from 25 participants in Scotland were measured. Trauma history and experience were assessed using the Childhood Trauma Questionnaire and Life Events Checklist. Trauma symptomatology was measured by the Impact of Event Scale. Interpersonal trust was measured using the Trust Scale. Trauma history and inflammatory biomarker concentrations were significant predictors of trauma symptomatology with trust as a covariate. Psychological and physiological responses after trauma seem strongly linked. Trust can mediate distress and physiology in adversity.

Journal Article Type Article
Acceptance Date Jan 18, 2022
Online Publication Date Mar 1, 2022
Publication Date 2023
Deposit Date Mar 25, 2022
Publicly Available Date Mar 2, 2023
Journal British Journal of Guidance & Counselling
Print ISSN 0306-9885
Electronic ISSN 1469-3534
Publisher Routledge
Peer Reviewed Peer Reviewed
Volume 51
Issue 4
Pages 528-545
Keywords Interpersonal trust, inflammation, adversity, psychological trauma, health, relational variables
Public URL


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