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Peer-delivery of a gender-specific smoking cessation intervention for women living in disadvantaged communities in Ireland We Can Quit2 (WCQ2) – a pilot cluster randomized controlled trial

Hayes, Catherine B.; Patterson, Jenny; Castello, Stefania; Burke, Emma; O�Connell, Nicola; Darker, Catherine D.; Bauld, Linda; Vance, Joanne; Ciblis, Aurelia; Dobbie, Fiona; Loudon, Kirsty; Devane, Declan; Dougall, Nadine


Catherine B. Hayes

Stefania Castello

Emma Burke

Nicola O�Connell

Catherine D. Darker

Linda Bauld

Joanne Vance

Aurelia Ciblis

Fiona Dobbie

Kirsty Loudon

Declan Devane


Introduction. The We Can Quit2 (WCQ2) pilot trial assessed the feasibility of ‘We Can Quit’ (WCQ), a community-based stop-smoking programme delivered by trained community facilitators, based on the socio-ecological framework and developed using a Community-based Participatory Research approach, targeting women living in socioeconomically disadvantaged (SED) areas of Ireland.
Methods. A pragmatic cluster RCT with a process evaluation was conducted in four matched pairs of SED districts (8-10,000 women per district). Districts were independently randomised to WCQ (group support + nicotine replacement therapy), or to individual support delivered by health professionals. Participants were adult women smokers interested in quitting, living or working in trial districts. Recruitment of districts and 194 women in four waves (49 women per wave); retention at 12-weeks and 6-months; fidelity to intervention delivery and acceptability of trial-related processes were assessed. Validated smoking abstinence at 12-week and 6-months post-intervention was recorded, missing data assumed as continued smoking.
Results. Eight districts were recruited. 125/188 (66.5%) eligible women consented. The 49 women target was reached in wave4. Retention at 12-weeks was [Intervention (I): 55.4%; Control (C): 51.7%], at 6-months, [I: 47.7%; C: 46.7%]. Smoking abstinence at 12-weeks was [I: 23.1%, (95% CI 14.5-34.7%); C: 13%, (95% CI 6.9-24.1%)]. 83.8% of session activities were delivered. Trial-related processes were acceptable to facilitators. Low literacy was highlighted as a barrier for participants’ acceptability.
Conclusions. WCQ was feasible to deliver by trained facilitators and indicated a positive direction in abstinence rates. Low literacy will need to be addressed in a future trial design.

Journal Article Type Article
Acceptance Date Nov 18, 2021
Online Publication Date Dec 23, 2021
Publication Date 2022-04
Deposit Date Nov 19, 2021
Publicly Available Date Dec 24, 2022
Print ISSN 1462-2203
Publisher Oxford University Press
Peer Reviewed Peer Reviewed
Volume 24
Issue 4
Pages 564-573
Public URL


Peer-delivery Of A Gender-specific Smoking Cessation Intervention For Women Living In Disadvantaged Communities In Ireland We Can Quit2 (WCQ2) – A Pilot Cluster Randomized Controlled Trial (accepted version) (462 Kb)

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