E Wallace
A cross-sectional survey to estimate the prevalence of family history of colorectal, breast and ovarian cancer in a Scottish general practice population
Wallace, E; Hinds, A; Campbell, H; Mackay, J; Cetnarskyj, R; Porteous, M E M
Authors
A Hinds
H Campbell
J Mackay
R Cetnarskyj
M E M Porteous
Abstract
A cross-sectional survey of all patients aged 30-65 in four general practices within one Local Health Care Co-operative in Fife, Scotland was undertaken to measure the prevalence of family history of colorectal, breast and ovarian cancer. A total of 7619 patients aged 30-65 responded to a postal questionnaire (response rate 59%). In all, 17% of respondents (1324, 95% Cl 16-18%) reported a relative affected by colorectal, breast or ovarian cancer. Of those, 6% (78, 95% CI 5-7%) met the Scottish guidelines for referral for genetics counselling. In all, 2% (24, 95% CI 1-3%) of all individuals with an affected relative had received genetic counselling and risk assessment. Of these, 25% (6, 95% CI 8-42%) met the moderate- or high-risk criteria for developing a cancer. In conclusion, the number of patients who are at a significantly increased risk of cancer on the basis of a family history is small (approximately 10 per General Practitioner (GP) list). It is therefore unrealistic to expect GPs to develop expertise in genetic risk estimation. A simple family history chart or pedigree is one way that a GP can, within the constraints of a GP consultation, determine which patients should be reassured and which referred to the local cancer genetic clinic.
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 29, 2004 |
Online Publication Date | Sep 21, 2004 |
Publication Date | 2004-10 |
Deposit Date | Mar 4, 2008 |
Publicly Available Date | Sep 12, 2023 |
Print ISSN | 0007-0920 |
Electronic ISSN | 1532-1827 |
Publisher | Cancer Research UK |
Peer Reviewed | Peer Reviewed |
Volume | 91 |
Pages | 1575-1579 |
DOI | https://doi.org/10.1038/sj.bjc.6602155 |
Keywords | Cross-sectional; Family cancer history; Genetic risk; Prevalence; GP consultation |
Public URL | http://researchrepository.napier.ac.uk/id/eprint/1581 |
Publisher URL | http://dx.doi.org/10.1038/sj.bjc.6602155 |
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A cross-sectional survey to estimate the prevalence of family history of colorectal, breast and ovarian cancer in a Scottish general practice population
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https://creativecommons.org/licenses/by-nc-sa/3.0/
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