Single LFP sorting for high-resolution brain-chip interfacing

Mahmud, Mufti; Travalin, Davide; Hussain, Amir; Girardi, Stefano; Maschietto, Marta; Felderer, Florian; Vassanelli, Stefano

Abstract

Understanding cognition has fascinated many neuroscientists and made them put their efforts in deciphering the brain’s information processing capabilities for cognition. Rodents perceive the environment through whisking during which tactile information is processed at the barrel columns of the somatosensory cortex (S1). The intra– and trans–columnar microcircuits in the barrel cortex segregate and integrate information during activation of this pathway. Local Field Potentials (LFPs) recorded from these barrel columns provide information about the microcircuits and the shape of the LFPs provide the fingerprint of the underlying neuronal network. Through a contour based sorting method, we could sort neuronal evoked LFPs recorded using high–resolution Electrolyte–Oxide–Semiconductor Field Effect Transistor (EOSFET) based neuronal probes. We also report that the latencies and amplitudes of the individual LFPs’ shapes vary among the different clusters generated by the method. The shape specific information of the single LFPs thus can be used in commenting on the underlying neuronal network generating those signals.

• Presentation Conference Type: Conference Paper (Published)
• Conference Name: BICS 2012: 5th International Conference on Brain Inspired Cognitive Systems
• Start Date: Jul 11, 2012
• End Date: Jul 14, 2012
• Publication Date: 2012
• Deposit Date: Oct 17, 2019
• Publisher: Springer
• Pages: 329-337
• Series Title: Lecture Notes in Computer Science
• Series Number: 7366
• Series ISSN: 0302-9743
• Book Title: Advances in Brain Inspired Cognitive Systems
• ISBN: 9783642315602
• DOI: https://doi.org/10.1007/978-3-642-31561-9_37
• Keywords: Neuronal probe; whisker stimulation; evoked brain activity; neuronal signal; neuronal signal analysis
• Public URL: http://researchrepository.napier.ac.uk/Output/1793285