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The Influence of Menstruation on Training Schedules in Well-Trained and Elite Female Mountain Bike, Road and Cyclocross Athletes (2023)
Journal Article
Aitkenhead, R., Kirkwood, L., Florida-James, G., & Ingram-Sills, L. (2023). The Influence of Menstruation on Training Schedules in Well-Trained and Elite Female Mountain Bike, Road and Cyclocross Athletes. Journal of Applied Sports Sciences, 2, 62-75. https://doi.org/10.37393/JASS.2023.02.6

Female physiology is unique and driven by fluctuations in sex hormones that regulate the menstrual cycle. These hormones present myriad mechanisms that may influence physiological systems, potentially implicating exercise performance. However, resear... Read More about The Influence of Menstruation on Training Schedules in Well-Trained and Elite Female Mountain Bike, Road and Cyclocross Athletes.

CIE Report: Bridging the gap (2023)
Report
Buchmann, A., Backhaus, C., Anderman, M., Plant O'Toole, E., Weaver, M., Neye, C., & Florida-James, G. (2023). CIE Report: Bridging the gap. Cycling Industries Europe

Ex Vivo treatment of coronary artery endothelial cells with serum post-exercise training offers limited protection against in vitro exposure to FEC-T chemotherapy (2023)
Journal Article
Mclaughlin, M., Hesketh, K. L., Horgan, S. L., Florida-James, G., Cocks, M., Strauss, J. A., & Ross, M. (2023). Ex Vivo treatment of coronary artery endothelial cells with serum post-exercise training offers limited protection against in vitro exposure to FEC-T chemotherapy. Frontiers in Physiology, 14, Article 1079983. https://doi.org/10.3389/fphys.2023.1079983

Background: Chemotherapy treatment for breast cancer associates with well-documented cardiovascular detriments. Exercise has shown promise as a potentially protective intervention against cardiac toxicity. However, there is a paucity of evidence for... Read More about Ex Vivo treatment of coronary artery endothelial cells with serum post-exercise training offers limited protection against in vitro exposure to FEC-T chemotherapy.

The future directions and trends for off road e-bike use and impact in Great Britain (2023)
Report
Ingram-Sills, L., Campbell, T., Kirkwood, L., & Florida-James, G. (2023). The future directions and trends for off road e-bike use and impact in Great Britain. British Cycling

The introduction of e-bikes into the cycling industry has resulted in a growing market, with sales demonstrating an increase exponentially over the last five years. Globally it is predicted that e-bikes will reach and potentially surpass 130 million... Read More about The future directions and trends for off road e-bike use and impact in Great Britain.

The Effects of Menstrual Cycle Phases on Running Repeated Sprint Ability (2022)
Journal Article
Di Nicola, S., Ferrier, B., Florida-James, G., & Kavaliauskas, M. (2022). The Effects of Menstrual Cycle Phases on Running Repeated Sprint Ability. International Journal of Strength and Conditioning, 2(1), https://doi.org/10.47206/ijsc.v2i1.137

Female participation in regular sport activities has increased in recent years, yet their representation in sports and exercise science literature remains low. This can be partly attributed to the complexities associated with the menstrual cycle (MC)... Read More about The Effects of Menstrual Cycle Phases on Running Repeated Sprint Ability.

Influence of menstruation on training schedules in female mountain bike athletes (2022)
Presentation / Conference
Aitkenhead, R., Kirkwood, L., Florida-James, G., & Ingram-Sills, L. (2022, April). Influence of menstruation on training schedules in female mountain bike athletes. Poster presented at The Biomedical Basis of Elite Performance 2022 (The Physiological Society), Nottingham

Female participation in elite sport is rising, the most recent Olympic games, Tokyo 2020, was the most gender-balanced games in history but research within female athletes is lacking. This study investigated if different phases of the menstrual cycle... Read More about Influence of menstruation on training schedules in female mountain bike athletes.

Trail use, motivations and environmental attitudes of 3780 European mountain bikers: what is sustainable? (2021)
Journal Article
Campbell, T., Kirkwood, L., McLean, G., Torsius, M., & Florida-James, G. (2021). Trail use, motivations and environmental attitudes of 3780 European mountain bikers: what is sustainable?. International Journal of Environmental Research and Public Health, 18(24), Article 12971. https://doi.org/10.3390/ijerph182412971

Background: The extent to which mountain biking impacts upon the environment is largely determined by rider behaviours. The purpose of this study was to gain a better understanding of how mountain bikers interact with the natural environment and expl... Read More about Trail use, motivations and environmental attitudes of 3780 European mountain bikers: what is sustainable?.

Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic (2021)
Journal Article
Mclaughlin, M., Florida-James, G., & Ross, M. (2021). Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic. Vascular Biology, 3(1), R106-R120. https://doi.org/10.1530/VB-21-0013

Breast cancer chemotherapy, although very potent against tumour tissue, results in significant cardiovascular toxicity. The focus of research in this area has been predominantly towards cardiotoxicity. There is limited evidence detailing the impact o... Read More about Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic.

Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age (2021)
Journal Article
Lithgow, H., Florida‐James, G., Ross, M., Duncan, G., & Leggate, M. (2021). Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age. Experimental Physiology, 106(7), 1460-1469. https://doi.org/10.1113/ep089480

Vitamin D plays a key role in the modulation of the immune system, mediated through the intracellular vitamin D receptor (VDR). Exercise has been shown to influence the activity and availability of the VDR. This study aimed to investigate the effect... Read More about Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age.

Immune Response of Elite Enduro Racers to Laboratory and Racing Environments: The Influence of Training Impulse and Vibration (2021)
Journal Article
Kirkwood, L., Ingram-Sills, L., Taylor, M. D., Malone, E., & Florida-James, G. (2021). Immune Response of Elite Enduro Racers to Laboratory and Racing Environments: The Influence of Training Impulse and Vibration. International Journal of Environmental Research and Public Health, 18(9), Article 4603. https://doi.org/10.3390/ijerph18094603

Introduction: Understanding the sport-specific immune response elicited during both training and competition is imperative to maximise athlete health and performance. Despite a growing population of professional enduro mountain bike athletes, little... Read More about Immune Response of Elite Enduro Racers to Laboratory and Racing Environments: The Influence of Training Impulse and Vibration.

Enduro World Series (EWS) Mountain Biking Injuries: A 2-year Prospective Study of 2010 Riders (2020)
Journal Article
Palmer, D., Florida-James, G., & Ball, C. (2020). Enduro World Series (EWS) Mountain Biking Injuries: A 2-year Prospective Study of 2010 Riders. International Journal of Sports Medicine, https://doi.org/10.1055/a-1320-1116

The sport of Enduro is the newest International Cycling Union sanctioned discipline in mountain biking. There are a number of studies reporting mountain biking injury to date however there are none detailing injuries in Enduro. The aim of the present... Read More about Enduro World Series (EWS) Mountain Biking Injuries: A 2-year Prospective Study of 2010 Riders.

The effects of age and acute aerobic and resistance exercise on circulating T lymphocyte vitamin D receptor (VDR) expression in healthy males (2019)
Presentation / Conference
Leggate, M., Florida-James, G., Ross, M., Jurevicius, M., Duncan, G., & Lithgow, H. (2019, December). The effects of age and acute aerobic and resistance exercise on circulating T lymphocyte vitamin D receptor (VDR) expression in healthy males. Presented at Future Physiology, Liverpool, UK

A low vitamin D status has been identified as an association risk factor in the etiology of numerous chronic diseases, with older adults identified as generally more deficient than younger populations. Exercise has been shown to act as a direct and i... Read More about The effects of age and acute aerobic and resistance exercise on circulating T lymphocyte vitamin D receptor (VDR) expression in healthy males.

Elite mountain bike enduro competition: a study of rider hand-arm vibration exposure (2019)
Journal Article
Kirkwood, L. A., Taylor, M. D., Ingram, L. A., Malone, E., & Florida-James, G. D. (2019). Elite mountain bike enduro competition: a study of rider hand-arm vibration exposure. Journal of Science and Cycling, 8(1), 18-25. https://doi.org/10.28985/1906.jsc.04

Limited information is currently available regarding the hand-arm vibration (HAV) exposure 5 for professional off-road cyclists. Previous reports have suggested that commuting and 6 recreational cyclists are at risk of exceeding exposure limit values... Read More about Elite mountain bike enduro competition: a study of rider hand-arm vibration exposure.

Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. (2019)
Journal Article
Montgomery, R., Paterson, A., Williamson, C., Florida-James, G., & Ross, M. D. (2019). Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. Frontiers in Physiology, https://doi.org/10.3389/fphys.2019.00447

Endothelial progenitor cells (EPCs) are a vasculogenic subset of progenitors, which play a key role in maintenance of endothelial integrity. These cells are exercise-responsive, and thus exercise may play a key role in vascular repair and maintenance... Read More about Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men..

The effect of acute exercise on T cell vitamin D receptor (VDR) expression in young and older males (2018)
Presentation / Conference
Leggate, M., Lithgow, H., Florida-James, G., & Barlow, P. (2018, July). The effect of acute exercise on T cell vitamin D receptor (VDR) expression in young and older males. Presented at 23rd Annual Congress of the European College of Sport Science (ECSS), Dublin, Ireland

A low vitamin D status has been identified as an association risk factor in the etiology of numerous chronic diseases, with older adults identified as generally more deficient than younger populations. Exercise has been shown to act as a direct and i... Read More about The effect of acute exercise on T cell vitamin D receptor (VDR) expression in young and older males.

Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men (2018)
Journal Article
Ross, M., Ingram, L., Taylor, G., Malone, E., Simpson, R. J., West, D., & Florida-James, G. (2018). Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men. Physiological Reports, 6(12), Article e13697. https://doi.org/10.14814/phy2.13697

Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative ability. CD31+ T-cells (angiogenic T-cells; TANG) possess highly angiogenic capa... Read More about Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men.

Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment (2018)
Journal Article
Boukelia, Z., Gomes, E. C., & Florida-James, G. D. (2018). Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment. Oxidative Medicine and Cellular Longevity, 2018, Article 3402143. https://doi.org/10.1155/2018/3402143

Purpose. The purpose of this study was to investigate the physiological and immunological response of highly trained runners to an intense bout of exercise performed at two different times of day, in a hot, humid environment. Methods. Using a crossov... Read More about Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment.

The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults (2018)
Journal Article
Lithgow, H. M., Florida-James, G., & Leggate, M. (2018). The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults. Physiological Reports, 6(9), Article e13684. https://doi.org/10.14814/phy2.13684

High intensity intermittent training (HIIT) has been shown to reduce the risk of chronic conditions including the development of type 2 diabetes mellitus (T2DM). Independently, a low vitamin D status has also been linked to the prevalence of T2DM. Th... Read More about The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults.