Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection
(2020)
Journal Article
Ho, J. S. Y., Angel, M., Ma, Y., Sloan, E., Wang, G., Martinez-Romero, C., …Marazzi, I. (2020). Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection. Cell, 181(7), 1502-1517. https://doi.org/10.1016/j.cell.2020.05.035
RNA viruses are a major human health threat. The life cycles of many highly pathogenic RNA viruses like influ-enza A virus (IAV) and Lassa virus depends on host mRNA, because viral polymerases cleave 50-m7G-cappedhost transcripts to prime viral mRNA... Read More about Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection.