All Outputs (2)

Rep provides a second motor at the replisome to promote duplication of protein-bound DNA (2009)
Journal Article
Guy, C., Atkinson, J., Gupta, M., Mahdi, A., Gwynn, E., Rudolph, C., …McGlynn, P. (2009). Rep provides a second motor at the replisome to promote duplication of protein-bound DNA. Molecular Cell, 36(4), 654-666. https://doi.org/10.1016/j.molcel.2009.11.009

Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by helicases with the ability to displace the block... Read More about Rep provides a second motor at the replisome to promote duplication of protein-bound DNA.

Bunyamwera orthobunyavirus S-segment untranslated regions mediate poly(A) tail-independent translation (2009)
Journal Article
Blakqori, G., van Knippenberg, I., & Elliott, R. (2009). Bunyamwera orthobunyavirus S-segment untranslated regions mediate poly(A) tail-independent translation. Journal of Virology, 83(8), https://doi.org/10.1128/jvi.02201-08

The mRNAs of Bunyamwera virus (BUNV), the prototype of the Bunyaviridae family, possess a 5′ cap structure but lack a 3′ poly(A) tail, a common feature of eukaryotic mRNAs that greatly enhances translation efficiency. Viral mRNAs also contain untrans... Read More about Bunyamwera orthobunyavirus S-segment untranslated regions mediate poly(A) tail-independent translation.