All Outputs (3)

Stability of the small γ-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus. (2009)
Journal Article
Fant, X., Gnadt, N., Haren, L., & Merdes, A. (2009). HCA66, a protein of the centrosome and the nucleolus. Journal of Cell Science, 122, 1134-1144. https://doi.org/10.1242/jcs.035238

To investigate changes at the centrosome during the cell cycle, we analyzed the composition of the pericentriolar material from unsynchronized and S-phase-arrested cells by gel electrophoresis and mass spectrometry. We identified HCA66, a protein... Read More about Stability of the small γ-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus..

NuMA is required for proper spindle assembly and chromosome alignment in prometaphase (2009)
Journal Article
Haren, L., Gnadt, N., Wright, M., & Merdes, A. (2009). NuMA is required for proper spindle assembly and chromosome alignment in prometaphase. BMC Research Notes, 2, Article 64. https://doi.org/10.1186/1756-0500-2-64

NuMA is a protein that has been previously shown to play a role in focusing microtubules at the mitotic spindle poles. However, most previous work relies on experimental methods that might cause dominant side effects on spindle formation, such as mic... Read More about NuMA is required for proper spindle assembly and chromosome alignment in prometaphase.

Hydrogenases in Desulfovibrio vulgaris Hildenborough: structural and physiologic characterisation of the membrane-bound [NiFeSe] hydrogenase (2005)
Journal Article
Valente, F. M. A., Oliveira, A. S. F., Gnadt, N., Pacheco, I., Coelho, A. V., Xavier, A. V., …Pereira, I. A. C. (2005). Hydrogenases in Desulfovibrio vulgaris Hildenborough: structural and physiologic characterisation of the membrane-bound [NiFeSe] hydrogenase. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 10(6), 667-682. https://doi.org/10.1007/s00775-005-0022-4

The genome of Desulfovibrio vulgaris Hildenborough (DvH) encodes for six hydrogenases (Hases), making it an interesting organism to study the role of these proteins in sulphate respiration. In this work we address the role of the [NiFeSe] Hase, found... Read More about Hydrogenases in Desulfovibrio vulgaris Hildenborough: structural and physiologic characterisation of the membrane-bound [NiFeSe] hydrogenase.