All Outputs (22)

A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation (2003)
Journal Article
Campbell, S., Campbell, S. A., Richards, T., Mui, E., Samuel, B., Coggins, J., …Roberts, C. (2004). A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation. International Journal for Parasitology, 34(1), 5-13. https://doi.org/10.1016/j.ijpara.2003.10.006

The shikimate pathway is essential for survival of the apicomplexan parasites Plasmodium falciparum, Toxoplasma gondii and Cryptosporidium parvum. As it is absent in mammals it is a promising therapeutic target. Herein, we describe the genes encoding... Read More about A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation.

Crystallization and preliminary X-ray analysis of shikimate dehydrogenase fromEscherichia coli (2000)
Journal Article
Maclean, J., Campbell, S. A., Pollock, K., Chackrewarthy, S., Coggins, J. R., & Lapthorn, A. J. (2000). Crystallization and preliminary X-ray analysis of shikimate dehydrogenase fromEscherichia coli. Acta crystallographica. Section D, Biological crystallography, 56(4), 512-515. https://doi.org/10.1107/s0907444900002377

Shikimate dehydrogenase from Escherichia coli has been crystallized by the vapour-diffusion method using ammonium sulfate as a precipitant. Mass spectrometry confirmed the purity of the enzyme and dynamic light scattering was used to find the appropr... Read More about Crystallization and preliminary X-ray analysis of shikimate dehydrogenase fromEscherichia coli.