The intermediate filament protein, vimentin, is a regulator of NOD2 activity.
(2013)
Journal Article
Stevens, C., Henderson, P., Nimmo, E. R., Soares, D. C., Dogan, B., Simpson, K. W., …Satsangi, J. (2013). The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut, 62, 695-707. https://doi.org/10.1136/gutjnl-2011-301775
Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Having previously identified vimentin as a novel NOD2-interacting protein, the a... Read More about The intermediate filament protein, vimentin, is a regulator of NOD2 activity..