Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis
(2009)
Journal Article
Wright, G. P., Notley, C. A., Xue, S. A., Bendle, G. M., Holler, A., Schumacher, T. N., …Stauss, H. J. (2009). Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis. Proceedings of the National Academy of Sciences, 106(45), 19078-19083. https://doi.org/10.1073/pnas.0907396106
Regulatory T cells (Tregs) can suppress a wide range of immune cells, making them an ideal candidate for the treatment of autoimmunity. The potential clinical translation of targeted therapy with antigen-specific Tregs is hampered by the difficulties... Read More about Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis.