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Clinical and physical signs for identification of impending and current water-loss dehydration in older people

Chassagne, Philippe; Olde Rikkert, Marcel GM; Hunter, Paul R.; Hooper, Lee; Attreed, Natalie J; Campbell, Wayne W; Channell, Adam M; Chasagne, Philippe; Culp, Kennith R; Fletcher, Stephen J; Fuller, Nigel; Gaspar, Phyllis M; Gilbert, Daniel J; Heathcote, Adam C; Lindner, Gregor; Mack, Gary W; Mentes, Janet C; Needham, Rowan A; Rikkert, Marcel G M Olde; Ranson, Sheila C; Ritz, Patrick; Rowat, Anne M; Smith, Alexandra C; Stookey, Jodi JD; Thomas, David R; Wakefield, Bonnie J; Ward, Sean; Potter, John F; Hunter, Paul R

Authors

Philippe Chassagne

Marcel GM Olde Rikkert

Paul R. Hunter

Lee Hooper

Natalie J Attreed

Wayne W Campbell

Adam M Channell

Philippe Chasagne

Kennith R Culp

Stephen J Fletcher

Nigel Fuller

Phyllis M Gaspar

Daniel J Gilbert

Adam C Heathcote

Gregor Lindner

Gary W Mack

Janet C Mentes

Rowan A Needham

Marcel G M Olde Rikkert

Sheila C Ranson

Patrick Ritz

Anne M Rowat

Alexandra C Smith

Jodi JD Stookey

David R Thomas

Bonnie J Wakefield

Sean Ward

John F Potter

Paul R Hunter



Contributors

Lee Hooper
Editor

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:
.To determine the diagnostic accuracy of state, minimally invasive clinical and physical signs (or sets of signs) to be used as screening tests for detecting impending or current water-loss dehydration, or both, in older people by systematically reviewing studies that have measured a reference standard and at least one index test in people aged 65 years and over.
.To assess the effect of different cut offs of index test results assessed using continuous data on sensitivity and specificity in diagnosis of impending or current water-loss dehydration.
.To identify clinical and physical signs that may be used in screening for impending or current water-loss dehydration in older people.
.To identify clinical and physical signs that are not useful in screening for impending or current water-loss dehydration in older people.
.To directly compare promising index tests (sensitivity ≥ 0.60 and specificity ≥ 0.75) where two or more are measured in a single study (direct comparison).
.To carry out an exploratory analysis to assess the value of combining the best three index tests where the three tests each have some predictive ability of their own, and individual studies include participants who had all three tests.
We will explore sources of heterogeneity of diagnostic accuracy of individual clinical and physical signs that show some evidence of discrimination by the reference standard used, cut off value for tests providing continuous data, type of participants (community-dwelling older people, those in residential care, and those in hospital), sex, and baseline prevalence of dehydration.
5. To carry out an exploratory analysis to assess the value of combining the best three index tests where the three tests each have some predictive ability of their own, and individual studies include participants who had all three tests.
We will explore sources of heterogeneity of diagnostic accuracy of individual clinical and physical signs that show some evidence of
discrimination by the reference standard used, cut off value for tests providing continuous data, type of participants (communitydwelling
older people, those in residential care, and those in hospital), sex, and baseline prevalence of dehydration.

Other Type Other
Online Publication Date Feb 15, 2012
Publication Date 2012
Deposit Date Mar 12, 2012
Journal Cochrane Database of Systematic reviews
Publisher Cochrane Collaboration
Peer Reviewed Peer Reviewed
Article Number CD009647
DOI https://doi.org/10.1002/14651858.cd009647
Keywords Elderly; water-loss; dehydration;
Public URL http://researchrepository.napier.ac.uk/id/eprint/5086
Publisher URL http://dx.doi.org/10.1002/14651858.CD009647
Contract Date Mar 12, 2012