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Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns. (2005)
Journal Article
Williams, K. R., NaWishart, J. G., Pitcairn, T. K. & Willis, D. (2005). Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns. American journal of mental retardation : AJMR. 110. . 387-392. . ISSN 0895-8017.

The ability of children with Down syndrome to recognize expressions of emotion was compared to performance in typically developing and nonspecific intellectual disability groups matched on either MA or a performance-related measure. Our goal was to (... Read More about Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns..

Hippocalcin functions as a calcium sensor in hippocampal LTD. (2005)
Journal Article
Palmer, C., Lim, W., Hastie, P. G. R., Toward, M., Korolchuk, V. I., Burbidge, S. A., …Henley, J. M. (2005). Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron, 47, 487-494. https://doi.org/10.1016/j.neuron.2005.06.014

It is not fully understood how NMDAR-dependent LTD causes Ca2+-dependent endocytosis of AMPARs. Here we show that the neuronal Ca2+ sensor hippocalcin binds the ?2-adaptin subunit of the AP2 adaptor complex and that along with GluR2 these coimmunopre... Read More about Hippocalcin functions as a calcium sensor in hippocampal LTD..

Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model. (2005)
Journal Article
Van Valckenborgh, E., Mincher, D., Di Salvo, A., Van Riet, I., Young, L., Van Camp, B., & Vanderkerken, K. (2005). Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model. Leukemia, 19, 1628-1633. https://doi.org/10.1038/sj.leu.2403866

Multiple myeloma (MM) is an incurable B-cell cancer characterised by the monoclonal proliferation of tumour cells in the bone marrow (BM). It has been described that matrix metalloproteinases (MMPs) and especially MMP-9 is secreted by MM cells. In th... Read More about Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model..

Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. (2005)
Journal Article
Dias, N., Goossens, J., Baldeyrou, B., Lansiaux, A., Colson, P., Di Salvo, A., …Bailly, C. (2005). Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. Bioconjugate Chemistry, 16, 949-958. https://doi.org/10.1021/bc050065x

We report the synthesis of an original series of oxoazabenzo[de]anthracenes conjugated to an amino acid: Ala, Phe, Pro, Lys, or Gly (4a-e, respectively). The compounds, derived from 1,8-dihydroxyanthracene-9,10-dione, were studied for DNA binding and... Read More about Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents..

The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. (2005)
Journal Article
Palmer, C., Cotton, L., & Henley, J. M. (2005). The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacological Reviews, 57, 253-277. https://doi.org/10.1124/pr.57.2.7

-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are of fundamental importance in the brain. They are responsible for the majority of fast excitatory synaptic transmission, and their overactivation is potently excitotoxic. Recent fi... Read More about The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors..

The impact of the shape of antibody recognition regions on the emergence of idiotypic networks. (2005)
Journal Article
Hart, E., & Ross, P. (2005). The impact of the shape of antibody recognition regions on the emergence of idiotypic networks. International Journal of Unconventional Computing, 1, 281-313

One of the components of an AIS algorithm that most distinguishes it from other paradigms is the use of an affinity funciton. However, for the most part, the implications of choosing a suitable matching rule and the likely effects on the algorithm fr... Read More about The impact of the shape of antibody recognition regions on the emergence of idiotypic networks..

Reducing diazepam prescribing for illicit drug users: a randomised control study. (2005)
Journal Article
Elliott, L., Glenday, J., Freeman, L., Ajeda, D., Johnston, B., Christie, M., & Ogston, S. (2005). Reducing diazepam prescribing for illicit drug users: a randomised control study. Drug and Alcohol Review, 24, 25-31. https://doi.org/10.1080/09595230500125138

Illicit drug users undergoing mandatory reductions in prescribed diazepam were randomly allocated to one of two methods of delivering psychological support to help reduce their prescription: a) an enhanced intervention consisting of skills training a... Read More about Reducing diazepam prescribing for illicit drug users: a randomised control study..