Chloride co-transporters as possible therapeutic targets for stroke (2016)
Journal Article
Martín-Aragón Baudel, M. A. S., Martín-Aragón Baudel, M. A. S., Poole, A. V., & Darlison, M. G. (2017). Chloride co-transporters as possible therapeutic targets for stroke. Journal of Neurochemistry, 140(2), 195-209. https://doi.org/10.1111/jnc.13901

Stroke is one of the major causes of death and disability worldwide. The major type of stroke is an ischaemic one, which is caused by a blockage that interrupts blood flow to the brain. There are currently very few pharmacological strategies to red... Read More about Chloride co-transporters as possible therapeutic targets for stroke.

Social cognition and paranoia in forensic inpatients with schizophrenia: A cross-sectional study (2016)
Journal Article
Bratton, H., O'Rourke, S., Tansey, L., & Hutton, P. (2016). Social cognition and paranoia in forensic inpatients with schizophrenia: A cross-sectional study. Schizophrenia Research, 184, 96-102. https://doi.org/10.1016/j.schres.2016.12.004

Background People diagnosed with schizophrenia have difficulties in emotion recognition and theory of mind, and these may contribute to paranoia. The aim of this study was to determine whether this relationship is evident in patients residing in a s... Read More about Social cognition and paranoia in forensic inpatients with schizophrenia: A cross-sectional study.

A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up (2016)
Journal Article
Wang, L., Chien, W. T., Yip, L. K., & Karatzias, T. (2016). A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up. Neuropsychiatric Disease and Treatment, 12, 3097-3110. https://doi.org/10.2147/ndt.s123239

Mindfulness-based interventions have been increasingly evidenced to be effective in different mental illnesses but limited in schizophrenia. This single-blind, multisite randomized controlled trial tested the effects of a mindfulness-based psychoeduc... Read More about A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up.

From Childhood Trauma to Self-Harm: An Investigation of Theoretical Pathways among Female Prisoners: Childhood Trauma and Self-Harm in Female Prisoners (2016)
Journal Article
Howard, R., Karatzias, T., Power, K., & Mahoney, A. (2017). From Childhood Trauma to Self-Harm: An Investigation of Theoretical Pathways among Female Prisoners: Childhood Trauma and Self-Harm in Female Prisoners. Clinical Psychology and Psychotherapy, 24(4), 942-951. https://doi.org/10.1002/cpp.2058

Despite empirical evidence suggesting complex associations between childhood trauma and self-harm, there is a dearth of research investigating this association in the female prison population. The current study explored pathways to self-harm followin... Read More about From Childhood Trauma to Self-Harm: An Investigation of Theoretical Pathways among Female Prisoners: Childhood Trauma and Self-Harm in Female Prisoners.

Depression and resilience mediate the relationship between traumatic life events and ill physical health: results from a population study (2016)
Journal Article
Karatzias, T., Jowett, S., Yan, E., Raeside, R., & Howard, R. (2016). Depression and resilience mediate the relationship between traumatic life events and ill physical health: results from a population study. Psychology, Health and Medicine, 22(9), 1021-1031. https://doi.org/10.1080/13548506.2016.1257814

We set out to investigate the mediating roles of depression, resilience, smoking, and alcohol use, in the relationship between potentially traumatic life events and objective and subjective, physical and mental health in a single study. A face-to-fac... Read More about Depression and resilience mediate the relationship between traumatic life events and ill physical health: results from a population study.

Posttraumatic stress disorder (PTSD) symptoms mediate the relationship between substance misuse and violent offending among female prisoners (2016)
Journal Article
Howard, R., Karatzias, T., Power, K., & Mahoney, A. (2017). Posttraumatic stress disorder (PTSD) symptoms mediate the relationship between substance misuse and violent offending among female prisoners. Social Psychiatry and Psychiatric Epidemiology, 52(1), 21-25. https://doi.org/10.1007/s00127-016-1293-5

Purpose Despite empirical evidence suggesting complex associations between psychological trauma, substance misuse, and violent offending, there is a dearth of research investigating these associations in the female prison population. Methods A cro... Read More about Posttraumatic stress disorder (PTSD) symptoms mediate the relationship between substance misuse and violent offending among female prisoners.

An initial psychometric assessment of an ICD-11 based measure of PTSD and complex PTSD (ICD-TQ): Evidence of construct validity (2016)
Journal Article
Karatzias, T., Cloitre, M., Brewin, C. R., Bisson, J. I., Roberts, N., Wilson, D., …Shevlin, M. (2016). An initial psychometric assessment of an ICD-11 based measure of PTSD and complex PTSD (ICD-TQ): Evidence of construct validity. Journal of Anxiety Disorders, 44, 73-79. https://doi.org/10.1016/j.janxdis.2016.10.009

Among the conditions following exposure to traumatic life events proposed by ICD-11 are Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). The primary aim of this study was to provide an assessment of the reliability and validity of a new... Read More about An initial psychometric assessment of an ICD-11 based measure of PTSD and complex PTSD (ICD-TQ): Evidence of construct validity.

Evidence of distinct profiles of Posttraumatic Stress Disorder (PTSD) and Complex Posttraumatic Stress Disorder (CPTSD) based on the new ICD-11 Trauma Questionnaire (ICD-TQ) (2016)
Journal Article
Karatzias, T., Shevlin, M., Fyvie, C., Hyland, P., Efthymiadou, E., Wilson, D., …Cloitre, M. (2017). Evidence of distinct profiles of Posttraumatic Stress Disorder (PTSD) and Complex Posttraumatic Stress Disorder (CPTSD) based on the new ICD-11 Trauma Questionnaire (ICD-TQ). Journal of Affective Disorders, 207, 181-187. https://doi.org/10.1016/j.jad.2016.09.032

Background The WHO International Classification of Diseases, 11th version (ICD-11), has proposed two related diagnoses following exposure to traumatic events; Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). We set out to explore whethe... Read More about Evidence of distinct profiles of Posttraumatic Stress Disorder (PTSD) and Complex Posttraumatic Stress Disorder (CPTSD) based on the new ICD-11 Trauma Questionnaire (ICD-TQ).

Early maladaptive schemas in adult survivors of interpersonal trauma: foundations for a cognitive theory of psychopathology (2016)
Journal Article
Karatzias, T., Jowett, S., Begley, A., & Deas, S. (2016). Early maladaptive schemas in adult survivors of interpersonal trauma: foundations for a cognitive theory of psychopathology. European Journal of Psychotraumatology Supplement, 7(1), 30713. https://doi.org/10.3402/ejpt.v7.30713

Background Although the association between psychological trauma and early maladaptive schemas (EMS) is well established in the literature, no study to date has examined the relationship of EMS to PTSD and psychopathologies beyond depression and anx... Read More about Early maladaptive schemas in adult survivors of interpersonal trauma: foundations for a cognitive theory of psychopathology.

The assessment and management of pain in patients with dementia in hospital settings: a multi-case exploratory study from a decision making perspective (2016)
Journal Article
Lichtner, V., Dowding, D., Allcock, N., Keady, J., Sampson, E. L., Briggs, M., …Closs, S. J. (2016). The assessment and management of pain in patients with dementia in hospital settings: a multi-case exploratory study from a decision making perspective. BMC Health Services Research, 16(1), https://doi.org/10.1186/s12913-016-1690-1

BACKGROUND: Pain is often poorly managed in people who have a dementia. Little is known about how this patient population is managed in hospital, with research to date focused mainly on care homes. This study aimed to investigate how pain is recogni... Read More about The assessment and management of pain in patients with dementia in hospital settings: a multi-case exploratory study from a decision making perspective.

Social responsiveness to inanimate entities: Altered white matter in a ‘social synaesthesia’ (2016)
Journal Article
Simner, J., Rehme, M., Carmichael, D., Bastin, M., Sprooten, E., McIntosh, A., …Zedler, M. (2016). Social responsiveness to inanimate entities: Altered white matter in a ‘social synaesthesia’. Neuropsychologia, 91, 282-289. https://doi.org/10.1016/j.neuropsychologia.2016.08.020

Judgments about personalities and social traits can be made by relatively brief exposure to animate living things. Here we show that unusual architecture in the microstructure of the human brain is related to atypical mental projections of personalit... Read More about Social responsiveness to inanimate entities: Altered white matter in a ‘social synaesthesia’.

Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial (2016)
Journal Article
Pyle, M., Schwannauer, M., Norrie, J., Kingdon, D., Gumley, A., Turkington, D., …Morrison, A. P. (2016). Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial. BMC Psychiatry, 16(280), https://doi.org/10.1186/s12888-016-0983-6

Background For around a third of people with a diagnosis of schizophrenia, the condition proves to respond poorly to treatment with many typical and atypical antipsychotics. This is commonly referred to as treatment-resistant schizophrenia. Clozap... Read More about Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial.

Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis (2016)
Journal Article
Stovell, D., Morrison, A. P., Panayiotou, M., & Hutton, P. (2016). Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis. British Journal of Psychiatry, 209(1), 23-28. https://doi.org/10.1192/bjp.bp.114.158931

BACKGROUND: In the UK almost 60% of people with a diagnosis of schizophrenia who use mental health services say they are not involved in decisions about their treatment. Guidelines and policy documents recommend that shared decision-making should be... Read More about Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis.

A proposal to support student therapists to develop compassion for self and others through Compassionate Mind Training (CMT) (2016)
Journal Article
Beaumont, E., & Hollins Martin, C. J. (2016). A proposal to support student therapists to develop compassion for self and others through Compassionate Mind Training (CMT). Arts in Psychotherapy, 50, 111/118. https://doi.org/10.1016/j.aip.2016.06.005

Purpose: By the very nature of the role, student therapists experience incidents that can be emotionally challenging. In response to such events, they may experience compassion fatigue, stress, burnout, and self-criticism, which in turn alters their... Read More about A proposal to support student therapists to develop compassion for self and others through Compassionate Mind Training (CMT).

Post-Traumatic Stress Disorder (PTSD) and Its relationship with perinatal bereavement: definitions, reactions, adjustments, and grief. (2016)
Book Chapter
Hollins Martin, C. J., & Martin, C. R. (2016). Post-Traumatic Stress Disorder (PTSD) and Its relationship with perinatal bereavement: definitions, reactions, adjustments, and grief. In C. R. Martin, V. R. Preedy, & V. B. Patel (Eds.), Comprehensive Guide to Post-Traumatic Stress Disorders (599-626). Springer International Publishing. https://doi.org/10.1007/978-3-319-08359-9_44

A small percentage of women present with diagnosed PTSD post childbirth; however, though this an area of increasing research and clinical interest generally, little is known about PTSD in relation to perinatal bereavement. Health professionals mus... Read More about Post-Traumatic Stress Disorder (PTSD) and Its relationship with perinatal bereavement: definitions, reactions, adjustments, and grief..

Different dimensions of cognitive style in typical and atypical cognition: new evidence and a new measurement tool (2016)
Journal Article
Mealor, A. D., Simner, J., Rothen, N., Carmichael, D. A., & Ward, J. (2016). Different dimensions of cognitive style in typical and atypical cognition: new evidence and a new measurement tool. PLOS ONE, 11(5), https://doi.org/10.1371/journal.pone.0155483

We developed the Sussex Cognitive Styles Questionnaire (SCSQ) to investigate visual and verbal processing preferences and incorporate global/local processing orientations and systemising into a single, comprehensive measure. In Study 1 (N = 1542), fa... Read More about Different dimensions of cognitive style in typical and atypical cognition: new evidence and a new measurement tool.

Positive Clinical Psychology and the Promotion of Happiness, Compassion, and Autonomy in People with Psychosis (2016)
Book Chapter
Hutton, P. (2016). Positive Clinical Psychology and the Promotion of Happiness, Compassion, and Autonomy in People with Psychosis. In A. M. Wood, & J. Johnson (Eds.), The Wiley Handbook of Positive Clinical Psychology, 245-260. Wiley

Positive clinical psychology and the promotion of happiness, compassion, and autonomy in people with psychosis.

Eye movement desensitization and reprocessing (EMDR) for DSM–5 posttraumatic stress disorder (PTSD) in adults with intellectual disabilities: A case study review. (2016)
Journal Article
Jowett, S., Karatzias, T., Brown, M., Grieve, A., Paterson, D., & Walley, R. (2016). Eye movement desensitization and reprocessing (EMDR) for DSM–5 posttraumatic stress disorder (PTSD) in adults with intellectual disabilities: A case study review. Psychological Trauma: Theory, Research, Practice, and Policy, 8(6), 709-719. https://doi.org/10.1037/tra0000101

Objective: People with intellectual disabilities may be at a greater risk for exposure to traumatic events and consequently develop posttraumatic stress disorder (PTSD). Although eye movement desensitization and reprocessing (EMDR) is an established... Read More about Eye movement desensitization and reprocessing (EMDR) for DSM–5 posttraumatic stress disorder (PTSD) in adults with intellectual disabilities: A case study review..

Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial (2016)
Journal Article
Morrison, A. P., Burke, E., Murphy, E., Pyle, M., Bowe, S., Varese, F., …Wood, L. J. (2016). Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial. Psychiatry Research, 240(30), 96-102. https://doi.org/10.1016/j.psychres.2016.04.024

We aimed to evaluate the feasibility of Cognitive Therapy (CT) as an intervention for internalised stigma in people with psychosis. We conducted a single-blind randomised controlled pilot trial comparing CT plus treatment as usual (TAU) with TAU only... Read More about Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial.

Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy–health psychology intervention feasibility study (2016)
Journal Article
Maidment, I. D., Shaw, R. L., Killick, K., Damery, S., Hilton, A., Wilcock, J., …Seare, N. (2016). Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy–health psychology intervention feasibility study. BMJ Open, 6(3), https://doi.org/10.1136/bmjopen-2015-010279

Introduction The inappropriate use of antipsychotics in people with dementia for behaviour that challenges is associated with an estimated 1800 deaths annually. However, solely focusing on antipsychotics may transfer prescribing to other equally dang... Read More about Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy–health psychology intervention feasibility study.