Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression (1994)
Journal Article
Coon, H., Hicks, A. A., Bailey, M. E., Hoff, M., Holik, J., Harvey, R. J., Johnson, K. J., Darlison, M. G., Reimherr, F., Wender, P., & Byerley, W. (1994). Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression. Psychiatric Genetics, 4(3), 185-191. https://doi.org/10.1097/00041444-199400430-00009

The gamma-aminobutyric acid (GABA) neurotransmitter system has been implicated in the pathogenesis of manic depression. Tests of this hypothesis can now be carried out due to the recent characterization of simple sequence repeat polymorphisms for the... Read More about Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression.

Molecular Characterization of GABA-Gated Chloride Ion Channels from Complex and Simple Nervous Systems (1994)
Book Chapter
Darlison, M. G. (1994). Molecular Characterization of GABA-Gated Chloride Ion Channels from Complex and Simple Nervous Systems. In C. Peracchia (Ed.), Handbook of Membrane Channels (303-315). Academic Press. https://doi.org/10.1016/b978-0-12-550640-3.50025-3

No abstract available.

Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons (1994)
Journal Article
Barnes Jr., E. M., Baumgartner, B. J., Harvey, R. J., & Darlison, M. G. (1994). Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons. Molecular Brain Research, 26(1-2), 9-17. https://doi.org/10.1016/0169-328x%2894%2990068-x

Research report
We have used quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) to analyze the expression of {GABAA} receptor subunit genes in cultured neurons from the chick embryo cerebral cortex. During maturation of the neuro... Read More about Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons.

Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain (1994)
Journal Article
Harvey, R. J., Schmitt, B., Hermans-Borgmeyer, I., Gundelfinger, E. D., Betz, H., & Darlison, M. G. (1994). Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain. Journal of Neurochemistry, 62(6), 2480-2483. https://doi.org/10.1046/j.1471-4159.1994.62062480.x

Abstract: We report the isolation of a full-length clone from a Drosophila melanogaster head cDNA library that encodes a 614-residue polypeptide that exhibits all of the features of a ligand-gated chloride-channel/receptor subunit. This polypeptide,... Read More about Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain.

Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis (1994)
Journal Article
Moffoot, A., O'Carroll, R. E., Murray, C., Dougall, N., Ebmeier, K., & Goodwin, G. M. (1994). Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis. Psychological Medicine, 24(01), 53. https://doi.org/10.1017/s0033291700026829

The effects upon regional brain function of infusing either saline or clonidine (1·5μg/kg) has been examined in 18 patients with alcoholic Korsakoff's psychosis using 99mTc-hexamethylpropyleneamineoxime (99mTc-HMPAO or 99mTc-Exametazime) and Single P... Read More about Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis.

Short-term effects of electroconvulsive treatment on the uptake of99mTc-Exametazime into brain in major depression shown with single photon emission tomography (1994)
Journal Article
Scott, A. I. F., Dougall, N., Ross, M., O'Carroll, R. E., Riddle, W., Ebmeier, K. P., & Goodwin, G. M. (1994). Short-term effects of electroconvulsive treatment on the uptake of99mTc-Exametazime into brain in major depression shown with single photon emission tomography. Journal of Affective Disorders, 30(1), 27-34. https://doi.org/10.1016/0165-0327%2894%2990148-1

Fifteen patients with major depression who were being treated with bilateral electroconvulsive treatment (ECT) were investigated before and 45 min after a single ECT using split-dose Single Photon Emission Tomography (SPET or SPECT) with 99mTc-Examet... Read More about Short-term effects of electroconvulsive treatment on the uptake of99mTc-Exametazime into brain in major depression shown with single photon emission tomography.