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Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis (2019)
Journal Article
Karatzias, T., Murphy, P., Cloitre, M., Bisson, J., Roberts, N., Shevlin, M., Hyland, P., Maercker, A., Ben-Ezra, M., Coventry, P., Mason-Roberts, S., Bradley, A., & Hutton, P. (2019). Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis. Psychological Medicine, 49(11), 1761-1775. https://doi.org/10.1017/S0033291719000436

Background: The 11th revision to the WHO International Classification of Diseases (ICD-11) identified Complex Posttraumatic Stress Disorder (CPTSD) as a new condition. There is a pressing need to identify effective CPTSD interventions. Methods: We co... Read More about Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis.

A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications (2018)
Journal Article
Paterson, C., Karatzias, T., Harper, S., Dougall, N., Dickson, A., & Hutton, P. (2019). A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications. British Journal of Clinical Psychology, 58(2), 211-230. https://doi.org/10.1111/bjc.12209

Objectives
Acute psychiatric inpatient wards are characterised by minimal provision of therapeutic activities and high readmission rates. Implementation of a comprehensive inpatient psychological intervention service has been recommended to overcome... Read More about A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications.

Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms? (2018)
Journal Article
Hutton, P., Di Rienzo, F., Turkington, D., Spencer, H., & Taylor, P. (2019). Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?. Schizophrenia Bulletin, 45(1), 37-47. https://doi.org/10.1093/schbul/sby153

Between 5 and 10 percent of people with psychosis will die by suicide, a rate which is 20 to 75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals... Read More about Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?.

The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis (2018)
Journal Article
Turner, D. T., MacBeth, A., Larkin, A., Moritz, S., Livingstone, K., Campbell, A., & Hutton, P. (2019). The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis. Schizophrenia Bulletin, 45(4), 784-793. https://doi.org/10.1093/schbul/sby136

Background
Evidence-based psychological interventions to support treatment decision-making capacity (‘capacity’) in psychosis do not currently exist. This study sought to establish whether reducing the extent to which this group form conclusions bas... Read More about The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis.

Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks (2018)
Journal Article
Woodrow, A., Sparks, S., Bobrovskaia, V., Paterson, C., Murphy, P., & Hutton, P. (2019). Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks. Psychological Medicine, 49(1), 32-48. https://doi.org/10.1017/S0033291718002660

To identify factors which may help or hinder decision-making ability in people with psychosis, we did a systematic review and meta-analysis of their performance on the Iowa and Cambridge Gambling Tasks. Analysis of 47 samples found they had moderatel... Read More about Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks.

A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder (2018)
Journal Article
Mahoney, A., Karatzias, T., & Hutton, P. (2018). A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder. Journal of Affective Disorders, https://doi.org/10.1016/j.jad.2018.09.059

Background: No previous meta-analyses have specifically investigated the effectiveness of psychological group therapy for symptoms associated with complex interpersonal trauma, including whether trauma memory processing (TMP) therapies are superior t... Read More about A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder.

Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome? (2018)
Journal Article
Spencer, H. M., McMenamin, M., Emsley, R., Turkington, D., Dunn, G., Morrison, A. P., Brabban, A., Hutton, P., & Dudley, R. (2018). Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?. Schizophrenia Research, 202, 385-386. https://doi.org/10.1016/j.schres.2018.07.016

This study investigated the effect of “dose” and the components of Cognitive Behavioral Therapy (CBT) on treatment effects. It is a secondary analysis of the ACTION (Assessment of Cognitive Therapy Instead of Neuroleptics) trial which investigated CB... Read More about Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?.

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial (2018)
Journal Article
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., Norrie, J., Hudson, J., Bowe, S. E., French, P., Byrne, R., Syrett, S., Dudley, R., McLeod, H. J., Griffiths, H., Barnes, T. R. E., Davies, L., Kingdon, D., Aydinlar, S., Courtley, J., …Tully, S. (2018). Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial. Lancet Psychiatry, 5(8), 633-643. https://doi.org/10.1016/s2215-0366%2818%2930184-6

Background
Although clozapine is the treatment of choice for treatment-refractory schizophrenia, 30–40% of patients have an insufficient response, and others are unable to tolerate it. Evidence for any augmentation strategies is scarce. We aimed to... Read More about Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial.

Systematic review and meta-analysis of factors that help or hinder treatment decision-making capacity in psychosis (2017)
Journal Article
Larkin, A., & Hutton, P. (2017). Systematic review and meta-analysis of factors that help or hinder treatment decision-making capacity in psychosis. British Journal of Psychiatry, 211(4), 205-215. https://doi.org/10.1192/bjp.bp.116.193458

Background: The evidence on factors that may influence treatment decisional capacity (‘capacity) in psychosis has yet to be comprehensively synthesised, which limits the development of effective strategies to improve or support it.
Aims: To determin... Read More about Systematic review and meta-analysis of factors that help or hinder treatment decision-making capacity in psychosis.

Loneliness in Psychosis: A Meta-analytical Review (2017)
Journal Article
Michalska da Rocha, B., Vasilopoulou, E., Rhodes, S., & Hutton, P. (2018). Loneliness in Psychosis: A Meta-analytical Review. Schizophrenia Bulletin, 44(1), 114-125. https://doi.org/10.1093/schbul/sbx036

Loneliness may be related to psychotic symptoms but a comprehensive synthesis of the literature in this area is lacking. The aim of the current study is to determine the magnitude and reliability of the loneliness-psychosis relationship in people dia... Read More about Loneliness in Psychosis: A Meta-analytical Review.

The feasibility and clinical benefits of improving facial affect recognition impairments in schizophrenia: Systematic review and meta-analysis (2017)
Journal Article
Bordon, N., O'Rourke, S., & Hutton, P. (2017). The feasibility and clinical benefits of improving facial affect recognition impairments in schizophrenia: Systematic review and meta-analysis. Schizophrenia Research, 188, 3-12. https://doi.org/10.1016/j.schres.2017.01.014

Background
People diagnosed with schizophrenia have significant difficulty accurately recognising emotions expressed by others. This may generate anomalous experiences which, if misinterpreted, could contribute to experiences of social defeat, psych... Read More about The feasibility and clinical benefits of improving facial affect recognition impairments in schizophrenia: Systematic review and meta-analysis.

Social cognition and paranoia in forensic inpatients with schizophrenia: A cross-sectional study (2016)
Journal Article
Bratton, H., O'Rourke, S., Tansey, L., & Hutton, P. (2016). Social cognition and paranoia in forensic inpatients with schizophrenia: A cross-sectional study. Schizophrenia Research, 184, 96-102. https://doi.org/10.1016/j.schres.2016.12.004

Background
People diagnosed with schizophrenia have difficulties in emotion recognition and theory of mind, and these may contribute to paranoia. The aim of this study was to determine whether this relationship is evident in patients residing in a s... Read More about Social cognition and paranoia in forensic inpatients with schizophrenia: A cross-sectional study.

Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial (2016)
Journal Article
Pyle, M., Schwannauer, M., Norrie, J., Kingdon, D., Gumley, A., Turkington, D., Byrne, R., Syrett, S., MacLennan, G., Dudley, R., McLeod, H. J., Griffiths, H., Bowe, S., Barnes, T. R. E., French, P., Hutton, P., Davies, L., & Morrison, A. P. (2016). Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial. BMC Psychiatry, 16(280), https://doi.org/10.1186/s12888-016-0983-6

Background

For around a third of people with a diagnosis of schizophrenia, the condition proves to respond poorly to treatment with many typical and atypical antipsychotics. This is commonly referred to as treatment-resistant schizophrenia. Clozap... Read More about Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial.

Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis (2016)
Journal Article
Stovell, D., Morrison, A. P., Panayiotou, M., & Hutton, P. (2016). Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis. British Journal of Psychiatry, 209(1), 23-28. https://doi.org/10.1192/bjp.bp.114.158931

BACKGROUND:
In the UK almost 60% of people with a diagnosis of schizophrenia who use mental health services say they are not involved in decisions about their treatment. Guidelines and policy documents recommend that shared decision-making should be... Read More about Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis.

Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial (2016)
Journal Article
Morrison, A. P., Burke, E., Murphy, E., Pyle, M., Bowe, S., Varese, F., Dunn, G., Chapman, N., Hutton, P., Welford, M., & Wood, L. J. (2016). Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial. Psychiatry Research, 240(30), 96-102. https://doi.org/10.1016/j.psychres.2016.04.024

We aimed to evaluate the feasibility of Cognitive Therapy (CT) as an intervention for internalised stigma in people with psychosis. We conducted a single-blind randomised controlled pilot trial comparing CT plus treatment as usual (TAU) with TAU only... Read More about Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial.

Service users’ experiences of the treatment decision-making process in psychosis: A phenomenological analysis (2016)
Journal Article
Stovell, D., Wearden, A., Morrison, A. P., & Hutton, P. (2016). Service users’ experiences of the treatment decision-making process in psychosis: A phenomenological analysis. Psychosis, 8(4), 311-323. https://doi.org/10.1080/17522439.2016.1145730

Objectives:
We aimed to explore the treatment decision-making experiences of
individuals with psychosis, and their implications for increasing service users autonomy through clinical practice and research.

Design:
A qualitative design was used... Read More about Service users’ experiences of the treatment decision-making process in psychosis: A phenomenological analysis.

In reply to Adams and colleagues (2015)
Journal Article
Hutton, P., Taylor, P. J., & Morrison, A. P. (2015). In reply to Adams and colleagues. Psychosis, 7(4), 367-367. https://doi.org/10.1080/17522439.2015.1093017

Dear Editor

We disagree with the Cochrane Schizophrenia Group’s (CSzG) self-assessment that the problems we identified (Hutton, Wood, Taylor, Irving & Morrison, 2014) in their reviews of popular antipsychotics for schizophrenia are not serious. We... Read More about In reply to Adams and colleagues.

Psychosis, delusions and the “jumping to conclusions” reasoning bias: a systematic review and meta-analysis (2015)
Journal Article
Taylor, P., Dudley, R., Wickham, S., & Hutton, P. (2015). Psychosis, delusions and the “jumping to conclusions” reasoning bias: a systematic review and meta-analysis. Schizophrenia Bulletin, 42(3), 652-665. https://doi.org/10.1093/schbul/sbv150

We did a systematic review and meta-analysis to investigate the magnitude and specificity of the “jumping to conclusions” (JTC) bias in psychosis and delusions. We examined the extent to which people with psychosis, and people with delusions specific... Read More about Psychosis, delusions and the “jumping to conclusions” reasoning bias: a systematic review and meta-analysis.

Confirming the structure of negative beliefs about psychosis and bipolar disorder: A confirmatory factor analysis study of the Personal Beliefs about Experience Questionnaire and Personal Beliefs about Illness Questionnaire (2015)
Journal Article
Taylor, P. J., Pyle, M., Schwannauer, M., Hutton, P., & Morrison, A. P. (2015). Confirming the structure of negative beliefs about psychosis and bipolar disorder: A confirmatory factor analysis study of the Personal Beliefs about Experience Questionnaire and Personal Beliefs about Illness Questionnaire. British Journal of Clinical Psychology, 54(4), 361-377. https://doi.org/10.1111/bjc.12079

Objectives:
Negative beliefs about psychosis and other mental health difficulties may contribute to depression and distress in individuals with these experiences. The Personal Beliefs about Experience Questionnaire (PBEQ) and Personal Beliefs about... Read More about Confirming the structure of negative beliefs about psychosis and bipolar disorder: A confirmatory factor analysis study of the Personal Beliefs about Experience Questionnaire and Personal Beliefs about Illness Questionnaire.