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The relationship between ICD-11 PTSD, complex PTSD and dissociative experiences (2019)
Journal Article
Hyland, P., Shevlin, M., Fyvie, C., Cloitre, M., & Karatzias, T. (2020). The relationship between ICD-11 PTSD, complex PTSD and dissociative experiences. Journal of Trauma and Dissociation, 21(1), 62-72. https://doi.org/10.1080/15299732.2019.1675113

Debate exists in the trauma literature regarding the role of dissociation in traumatic stress disorders. With the release of the new ICD-11 diagnostic guideline for posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD), this issue warrants fu... Read More about The relationship between ICD-11 PTSD, complex PTSD and dissociative experiences.

Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis (2019)
Journal Article
Staines, K., Ikpegbu, E., Törnqvist, A., Dillon, S., Javaheri, B., Amin, A. K., …Farquharson, C. (2019). Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskeletal Disorders, 20, Article 344 (2019). https://doi.org/10.1186/s12891-019-2731-9

Background: Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, we examine whether disruption... Read More about Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis.

Differentiating Symptom Profiles of ICD-11 PTSD, Complex PTSD and Borderline Personality Disorder: A Latent Class Analysis in a Multiply Traumatised Sample (2019)
Journal Article
Jowett, S., Karatzias, T., Shevlin, M., & Albert, I. (2020). Differentiating Symptom Profiles of ICD-11 PTSD, Complex PTSD and Borderline Personality Disorder: A Latent Class Analysis in a Multiply Traumatised Sample. Personality Disorders: Theory, Research, and Treatment, 11(1), 36-45. https://doi.org/10.1037/per0000346

Background: Complex PTSD (CPTSD) has been included as a diagnostic category in the ICD-11 consisting of six symptom clusters; the three PTSD criteria of Re-experiencing, Avoidance, and Hypervigilance, in addition to three Disturbances of Self-Organis... Read More about Differentiating Symptom Profiles of ICD-11 PTSD, Complex PTSD and Borderline Personality Disorder: A Latent Class Analysis in a Multiply Traumatised Sample.

The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK (2019)
Journal Article
Hooper, K. M., Casanova, V., Kemp, S., Staines, K. A., Satsangi, J., Barlow, P. G., …Stevens, C. (2019). The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK. Inflammatory Bowel Diseases, 25(9), 1481-1496. https://doi.org/10.1093/ibd/izz039

Background Genetic studies have strongly linked autophagy to Crohn's disease (CD) and stimulating autophagy in CD patients may be therapeutically beneficial. The aim of this study was to evaluate the effect of current inflammatory bowel disease (IBD)... Read More about The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK.

Using Foucauldian Discourse Analysis to Analyze Young Women’s Constructions of the Human Papillomavirus Vaccine (2018)
Journal Article
Gray Brunton, C., Todorova, I., Petrova, D., Carnegie, E., & Whittaker, A. (2018). Using Foucauldian Discourse Analysis to Analyze Young Women’s Constructions of the Human Papillomavirus Vaccine. Sage Research Methods Cases, https://doi.org/10.4135/9781526440235

This case study introduces the reader to Foucauldian discourse analysis (FDA) as applied to a cross-cultural project around young women’s constructions of the Human Papillomavirus (HPV) vaccine. We introduce common qualitative research approaches in... Read More about Using Foucauldian Discourse Analysis to Analyze Young Women’s Constructions of the Human Papillomavirus Vaccine.

Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease (2018)
Journal Article
Hooper, K. M., Barlow, P. G., Henderson, P., & Stevens, C. (2019). Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 25(4), 661-671. https://doi.org/10.1093/ibd/izy380

Inflammatory Bowel Disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis, is characterised by chronic inflammation of the gastrointestinal tract. Aetiology involves a combination of genetic and environmental factors resulting in a... Read More about Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease.

An evaluation of mainstream type 2 diabetes educational programmes in relation to the needs of people with intellectual disabilities: A systematic review of the literature (2018)
Journal Article
Brown, M. J., Maine, A., Brown, M. .., Dickson, A., & Truesdale, M. (2018). An evaluation of mainstream type 2 diabetes educational programmes in relation to the needs of people with intellectual disabilities: A systematic review of the literature. Journal of Applied Research in Intellectual Disabilities, 32(2), 256-279. https://doi.org/10.1111/jar.12544

Background Risk reduction and self?management programs for type 2 diabetes (T2D) are commonplace. However, little is known about their appropriateness for people with intellectual disabilities (ID). This review evaluates successful components and th... Read More about An evaluation of mainstream type 2 diabetes educational programmes in relation to the needs of people with intellectual disabilities: A systematic review of the literature.

Holistic needs assessment in brain cancer patients: A systematic review of available tools (2018)
Journal Article
Afseth, J., Neubeck, L., Karatzias, T., & Grant, R. (2019). Holistic needs assessment in brain cancer patients: A systematic review of available tools. European Journal of Cancer Care, 28(3), https://doi.org/10.1111/ecc.12931

This systematic review describes tools which could be considered for use for holistic needs assessment in Brain Cancer. MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and PsycINFO were searched. Studies where included wh... Read More about Holistic needs assessment in brain cancer patients: A systematic review of available tools.

Colorectal Cancer in People with Intellectual Disabilities (2018)
Journal Article
Willis, D., Samalin, E., & Satgé, D. (2018). Colorectal Cancer in People with Intellectual Disabilities. Oncology, 95(6), 323-336. https://doi.org/10.1159/000492077

People with intellectual disabilities (PWIDs) are now living longer; thus, the incidence of cancer within this population is increasing. Available data indicate an excess of digestive tract cancers in PWIDs, but colorectal cancer has rarely been spec... Read More about Colorectal Cancer in People with Intellectual Disabilities.

The challenges of type 1 diabetes and new psychoactive substance misuse (2018)
Journal Article
Charlton, J., Albanese, A., & Brodie, L. (2018). The challenges of type 1 diabetes and new psychoactive substance misuse. Practical Diabetes, 35(3), 81-85a. https://doi.org/10.1002/pdi.2168

Substance misuse, specifically novel psychoactive substances (NPSs), can have multiple effects on physical and psychological health and well-being. This is of particular concern to people with type 1 diabetes (T1DM) as their use may impact on effecti... Read More about The challenges of type 1 diabetes and new psychoactive substance misuse.

The experience of type 2 diabetes self-management in adults with intellectual disabilities and their caregivers: A review of the literature using meta-aggregative synthesis and an appraisal of rigour (2018)
Journal Article
Maine, A., Brown, M., Dickson, A., & Truesdale, M. (2020). The experience of type 2 diabetes self-management in adults with intellectual disabilities and their caregivers: A review of the literature using meta-aggregative synthesis and an appraisal of rigour. Journal of Intellectual Disabilities, 24(2), 253-267. https://doi.org/10.1177/1744629518774172

People with intellectual disabilities (ID) experience significant barriers to diabetes self-management (DSM), yet there remains a paucity of research within this population. An overview of the literature on people with ID and their caregivers’ exper... Read More about The experience of type 2 diabetes self-management in adults with intellectual disabilities and their caregivers: A review of the literature using meta-aggregative synthesis and an appraisal of rigour.

Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study (2018)
Journal Article
Lone, N. I., Lee, R., Salisbury, L., Donaghy, E., Ramsay, P., Rattray, J., & Walsh, T. S. (2019). Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study. Thorax, 75(11), 1046-1054. https://doi.org/10.1136/thoraxjnl-2017-210822

Background Intensive care unit survivors experience high levels of morbidity after hospital discharge and are at high risk of unplanned hospital readmission. Identifying those at highest-risk before hospital discharge may allow targeting of novel ri... Read More about Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study.

The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study (2018)
Journal Article
Dobson, C., Russell, A., Brown, S., & Rubin, G. (2018). The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study. European Journal of Cancer Care, 27(2), Article e12815. https://doi.org/10.1111/ecc.12815

Prolonged diagnostic intervals are associated with poorer outcomes, and the patient interval appears to be a substantial contributor to the overall length of the diagnostic interval. This study sought to understand how the broader context of people's... Read More about The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study.

Effectiveness, acceptability and usefulness of mobile applications for cardiovascular disease self-management: Systematic review with meta-synthesis of quantitative and qualitative data (2018)
Journal Article
Coorey, G. M., Coorey, G. M., Neubeck, L., Mulley, J., & Redfern, J. (2018). Effectiveness, acceptability and usefulness of mobile applications for cardiovascular disease self-management: Systematic review with meta-synthesis of quantitative and qualitative data. European Journal of Preventive Cardiology, 25(5), 505-521. https://doi.org/10.1177/2047487317750913

Background: Mobile technologies are innovative, scalable approaches to reducing risk of cardiovascular disease (CVD) but evidence related to effectiveness and acceptability remains limited. We aimed to explore the effectiveness, acceptability and us... Read More about Effectiveness, acceptability and usefulness of mobile applications for cardiovascular disease self-management: Systematic review with meta-synthesis of quantitative and qualitative data.

Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation (2017)
Journal Article
Monahan, M., Jowett, S., Lovibond, K., Gill, P., Godwin, M., Greenfield, S., …McManus, R. J. (2017). Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation. Hypertension, https://doi.org/10.1161/hypertensionaha.117.10244

Clinical guidelines in the United States and United Kingdom recommend that individuals with suspected hypertension should have ambulatory blood pressure (BP) monitoring to confirm the diagnosis. This approach reduces misdiagnosis because of white coa... Read More about Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation.

Control of Antimicrobial Resistance Requires an Ethical Approach (2017)
Journal Article
Parsonage, B., Hagglund, P. K., Keogh, L., Wheelhouse, N., Brown, R. E., & Dancer, S. J. (2017). Control of Antimicrobial Resistance Requires an Ethical Approach. Frontiers in Microbiology, 8, https://doi.org/10.3389/fmicb.2017.02124

Ethical behavior encompasses actions that benefit both self and society. This means that tackling antimicrobial resistance (AMR) becomes an ethical obligation, because the prospect of declining anti-infectives affects everyone. Without preventive act... Read More about Control of Antimicrobial Resistance Requires an Ethical Approach.

Preferential activation of HIF-2? adaptive signalling in neuronal-like cells in response to acute hypoxia (2017)
Journal Article
Martín-Aragón Baudel, M. A. S., Rae, M. T., Darlison, M. G., Poole, A. V., & Fraser, J. A. (2017). Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia. PLOS ONE, 12(10), Article e0185664. https://doi.org/10.1371/journal.pone.0185664

Stroke causes severe neuronal damage as disrupted cerebral blood flow starves neurons of oxygen and glucose. The hypoxia inducible factors (HIF-1? and HIF-2?) orchestrate oxygen homeostasis and regulate specific aspects of hypoxic adaptation. Here we... Read More about Preferential activation of HIF-2? adaptive signalling in neuronal-like cells in response to acute hypoxia.

A systematic review of cardiac rehabilitation registries (2017)
Journal Article
Poffley, A., Thomas, E., Grace, S. L., Neubeck, L., Gallagher, R., Niebauer, J., & O’Neil, A. (2017). A systematic review of cardiac rehabilitation registries. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487317724576

Introduction: Despite cardiac rehabilitation (CR) being recommended in clinical practice guidelines internationally these services are under-utilised, programs are not standardised and quality improvement methods and outcomes are rarely published. Na... Read More about A systematic review of cardiac rehabilitation registries.

Is there an app for that? Mobile phones and secondary prevention of cardiovascular disease (2017)
Journal Article
Neubeck, L., Cartledge, S., Dawkes, S., & Gallagher, R. (2017). Is there an app for that? Mobile phones and secondary prevention of cardiovascular disease. Current Opinion in Cardiology, 32(5), 567-571. https://doi.org/10.1097/hco.0000000000000428

Purpose of review Advances in technology coupled with increased penetration of mobile phones and smart devices are rapidly changing healthcare delivery. Mobile phone applications (‘apps’), text messages, and Internet platforms used alone or in combi... Read More about Is there an app for that? Mobile phones and secondary prevention of cardiovascular disease.