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Preferential activation of HIF-2? adaptive signalling in neuronal-like cells in response to acute hypoxia (2017)
Journal Article
Martín-Aragón Baudel, M. A. S., Rae, M. T., Darlison, M. G., Poole, A. V., & Fraser, J. A. (2017). Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia. PLOS ONE, 12(10), Article e0185664. https://doi.org/10.1371/journal.pone.0185664

Stroke causes severe neuronal damage as disrupted cerebral blood flow starves neurons of oxygen and glucose. The hypoxia inducible factors (HIF-1? and HIF-2?) orchestrate oxygen homeostasis and regulate specific aspects of hypoxic adaptation. Here we... Read More about Preferential activation of HIF-2? adaptive signalling in neuronal-like cells in response to acute hypoxia.

Oestrogen formation and connective tissue growth factor expression in rat granulosa cells (2006)
Journal Article
Harlow, C. R., Bradshaw, A. C., Rae, M. T., Shearer, K. D., & Hillier, S. G. (2007). Oestrogen formation and connective tissue growth factor expression in rat granulosa cells. Journal of Endocrinology, 192(1), 41-52. https://doi.org/10.1677/joe.1.06689

Ovarian follicular development involves continual remodelling of the extracellular matrix (ECM) forming the basement membrane and intercellular framework that support granulosa cell (GC) growth and differentiation. Insight into the molecular regulati... Read More about Oestrogen formation and connective tissue growth factor expression in rat granulosa cells.