Outputs (6)

Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa (2024)
Journal Article
Orzel, D., Ravald, H., Dillon, A., Rantala, J., Wiedmer, S. K., & Russo, G. (2024). Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa. Journal of Chromatography A, 1734, Article 465286. https://doi.org/10.1016/j.chroma.2024.465286

This study pioneers a comparison of the application of biomimetic techniques, immobilised artificial membrane liquid chromatography (IAM LC) and liposome electrokinetic capillary chromatography (LEKC), for the prediction of pulmonary drug permeabilit... Read More about Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa.

β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting (2024)
Journal Article
Baghestani, S., Haldin, C., Kosijer, P., Alam, C. M., & Toivola, D. M. (2024). β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting. American Journal of Physiology - Cell Physiology, 327(2), C462-C476. https://doi.org/10.1152/ajpcell.00123.2024

Islet β-cell dysfunction is an underlying factor for type I diabetes (T1D) development. Insulin sensing and secretion are tightly regulated in β-cells at multiple subcellular levels. The epithelial intermediate filament (IF) protein keratin (K) 8 is... Read More about β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting.

Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation (2023)
Journal Article
Duncan, W. C., Nicol, L. M., O’Hare, R., Witherington, J., Miranda, J. A., Campbell, B. K., Thomas, J. L., & Rae, M. T. (2023). Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation. Frontiers in Endocrinology, 14, Article 1285269. https://doi.org/10.3389/fendo.2023.1285269

Introduction: Polycystic ovary syndrome (PCOS) seems to be associated with increased ovarian sympathetic nerve activity and in rodent models of PCOS reducing the sympathetic drive to the ovary, through denervation or neuromodulation, improves ovulati... Read More about Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation.

Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland (2023)
Journal Article
Garden, C. L. P. (2023). Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland. British Journal of Biomedical Science, 80, Article 11654. https://doi.org/10.3389/bjbs.2023.11654

Biomedical sciences graduates are employed in a variety of different settings and form a significant part of the Life Sciences sector workforce in Scotland. Their degrees should equip them with the skills and knowledge to not only enter the workplace... Read More about Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland.

Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq (2023)
Journal Article
Stokes, T., Cen, H. H., Kapranov, P., Gallagher, I. J., Pitsillides, A. A., Volmar, C., Kraus, W. E., Johnson, J. D., Phillips, S. M., Wahlestedt, C., & Timmons, J. A. (2023). Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq. Advanced Genetics, 4(2), Article 2200024. https://doi.org/10.1002/ggn2.202200024

Sequencing the human genome empowers translational medicine, facilitating transcriptome-wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are used to study the bulk transcriptome; but now short-read RNA sequenc... Read More about Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq.

Isolation of Streptococcus Mutans and its Bacteriophage from Human Plaque Samples (2019)
Journal Article
Ahmed, H., Flockhart, A., Foley, S., & Foley, J. (2019). Isolation of Streptococcus Mutans and its Bacteriophage from Human Plaque Samples. Saudi Journal of Oral and Dental Research, 4(8), 561-564. https://doi.org/10.21276/sjodr.2019.4.8.10

Background: Streptococcus mutans (S. mutans) is one of the main agents of caries formation, mainly because of the ability to form biofilms on the tooth surface. Bacteriophage of S. mutans are viruses that can attack and limit the pathogenic activity... Read More about Isolation of Streptococcus Mutans and its Bacteriophage from Human Plaque Samples.