Outputs (141)

Evidence for rapid, tide-related shifts in the microbiome of the coral Coelastrea aspera (2017)
Journal Article
Sweet, M. J., Brown, B. E., Dunne, R. P., Singleton, I., & Bulling, M. (2017). Evidence for rapid, tide-related shifts in the microbiome of the coral Coelastrea aspera. Coral Reefs, 36(3), 815-828. https://doi.org/10.1007/s00338-017-1572-y

Shifts in the microbiome of the intertidal coral Coelastrea aspera (formally known as Goniastrea aspera) from Phuket, Thailand were noted over the course of a four day period of spring tides. During this time corals were naturally exposed to high tem... Read More about Evidence for rapid, tide-related shifts in the microbiome of the coral Coelastrea aspera.

Isolation of Indigenous Hydrocarbon Transforming Bacteria from Oil Contaminated Soils in Libya: Selection for Use as Potential Inocula for Soil Bioremediation (2017)
Journal Article
Hakima, A., & Singleton, I. (2017). Isolation of Indigenous Hydrocarbon Transforming Bacteria from Oil Contaminated Soils in Libya: Selection for Use as Potential Inocula for Soil Bioremediation. International journal of environmental bioremediation & biodegradation, 5(1), 8-17. https://doi.org/10.12691/ijebb-5-1-2

The Libyan oil industry has left a significant legacy of contamination and methods are required to remediate oil-contaminated soils in the area. In this work hydrocarbon utilizing microorganisms were isolated and identified from contaminated soil sam... Read More about Isolation of Indigenous Hydrocarbon Transforming Bacteria from Oil Contaminated Soils in Libya: Selection for Use as Potential Inocula for Soil Bioremediation.

Listeria monocytogenes (2017)
Book Chapter
Rees, C., Doyle, L., & Taylor, C. (2017). Listeria monocytogenes. In Foodborne Diseases (253-276). (3rd). Elsevier. https://doi.org/10.1016/b978-0-12-385007-2.00012-7

Listeria monocytogenes was first described in 1923. Before 1982, L. monocytogenes was recognized as a cause of abortions and encephalitis in many animals (particularly cattle and sheep) and was thought to be associated with contaminated animal feed o... Read More about Listeria monocytogenes.

Antibiotic prescribing: the consequences of getting it wrong (2016)
Journal Article
Dancer, S. J. (2016). Antibiotic prescribing: the consequences of getting it wrong. Clinical Focus Primary Care, 10(2), 62-71

Antibiotics were one of the most important discoveries last century. As with all drugs, however, they are associated with adverse effects. This article reviews how inappropriate antibiotic prescribing not only fails to cure an infected patient; it ma... Read More about Antibiotic prescribing: the consequences of getting it wrong.

Microbiology of Raw Milk (2016)
Presentation / Conference Contribution
Foley, S. (2016, October). Microbiology of Raw Milk. Presented at Technical Conference - Milk and Cheese Microbiology, Edinburgh

Dos and don’ts for hospital cleaning (2016)
Journal Article
Dancer, S. J. (2016). Dos and don’ts for hospital cleaning. Current Opinion in Infectious Diseases, 29(4), 415-423. https://doi.org/10.1097/qco.0000000000000289

Purpose of review: More evidence is emerging on the role of cleaning and decontamination for reducing hospital-acquired infection. Timely and adequate removal of environmental pathogens leads to measurable clinical benefits for patients. This article... Read More about Dos and don’ts for hospital cleaning.

Ovine trophoblasts express cathelicidin host defence peptide in response to infection (2016)
Journal Article
Coyle, C., Wheelhouse, N., Jacques, M., Longbottom, D., Svoboda, P., Pohl, J., Colin Duncan, W., Rae, M. T., & Barlow, P. G. (2016). Ovine trophoblasts express cathelicidin host defence peptide in response to infection. Journal of Reproductive Immunology, 117, 10-16. https://doi.org/10.1016/j.jri.2016.06.006

Cationic host defence peptides (CHDP; also known as antimicrobial peptides) are key components of the immune response in the female reproductive tract. The role of the placental trophoblast in ovine host defence remains poorly understood. This study... Read More about Ovine trophoblasts express cathelicidin host defence peptide in response to infection.

Antiviral host defence peptides. (2016)
Book Chapter
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016). Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents (57-94). Springer. https://doi.org/10.1007/978-3-319-32949-9_3

The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The antiviral activity of cationic host defence peptides is of significant interest... Read More about Antiviral host defence peptides..

Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial (2016)
Journal Article
Hall, L., Farrington, A., Mitchell, B. G., Barnett, A. G., Halton, K., Allen, M., Page, K., Gardner, A., Havers, S., Bailey, E., Dancer, S. J., Riley, T. V., Gericke, C. A., Paterson, D. L., & Graves, N. (2016). Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial. Implementation Science, 11(1), Article 44. https://doi.org/10.1186/s13012-016-0406-6

Background
The Researching Effective Approaches to Cleaning in Hospitals (REACH) study will generate evidence about the effectiveness and cost-effectiveness of a novel cleaning initiative that aims to improve the environmental cleanliness of hospita... Read More about Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial.

MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells (2016)
Journal Article
Storrie, S., Longbottom, D., Barlow, P. G., & Wheelhouse, N. (2016). MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells. PLOS ONE, 11(3), Article e0152193. https://doi.org/10.1371/journal.pone.0152193

Background
Waddlia chondrophila (W. chondrophila) is an emerging agent of respiratory and reproductive disease in humans and cattle. The organism is a member of the order Chlamydiales, and shares many similarities at the genome level and in growth s... Read More about MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells.

Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from surfaces’ (2015)
Journal Article
Dancer, S. (2016). Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from surfaces’. Journal of Hospital Infection, 92(2), 208-209. https://doi.org/10.1016/j.jhin.2015.10.020

Letter to Editor.

Refers to - J.-Y. Maillard, S.A. Sattar, C. Bradley
Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from surfaces’
Journal of Hospital Infection, Volume 92, Issue 2, February 201... Read More about Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from surfaces’.

Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response (2014)
Journal Article
Wheelhouse, N., Coyle, C., Barlow, P. G., Mitchell, S., Greub, G., Baszler, T., Rae, M. T., & Longbottom, D. (2014). Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response. PLOS ONE, 9(7), Article e102386. https://doi.org/10.1371/journal.pone.0102386

BACKGROUND

Waddlia chondrophila (W. chondrophila) is an emerging abortifacient organism which has been identified in the placentae of humans and cattle. The organism is a member of the order Chlamydiales, and shares many similarities at the genome... Read More about Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response.

Antiviral potential of cathelicidins (2013)
Journal Article
Barlow, P. G., Findlay, E. G., Currie, S. M., & Davidson, D. J. (2014). Antiviral potential of cathelicidins. Future Microbiology, 9(1), 55-73. https://doi.org/10.2217/fmb.13.135

The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of innate immunity has expanded over recent years, knowledge of natural host de... Read More about Antiviral potential of cathelicidins.

Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status (2012)
Journal Article
Prach, M., Stone, V., & Proudfoot, L. (2012). Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status. Toxicology and Applied Pharmacology, 266(1), 19-26. https://doi.org/10.1016/j.taap.2012.10.020

Zinc oxide (ZnO) particle induced cytotoxicity was dependent on size, charge and solubility, factors which at sublethal concentrations may influence the activation of the human monocytic cell line THP1. ZnO nanoparticles (NP; average diameter 70 nm)... Read More about Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status.

Dynamics of bacterial communities in relation to soil aggregate formation during the decomposition of 13C-labelled rice straw (2011)
Journal Article
Blaud, A., Lerch, T., Chevallier, T., Nunan, N., Chenu, C., & Brauman, A. (2012). Dynamics of bacterial communities in relation to soil aggregate formation during the decomposition of 13C-labelled rice straw. Applied Soil Ecology, 53, 1-9. https://doi.org/10.1016/j.apsoil.2011.11.005

The addition of fresh organic matter is known to modify both microbial community structure and soil aggregation. The objective of this study was to understand the relationship between the dynamics of the soil microbial community structure in relation... Read More about Dynamics of bacterial communities in relation to soil aggregate formation during the decomposition of 13C-labelled rice straw.

Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37 (2011)
Journal Article
Barlow, P. G., Svoboda, P., Mackellar, A., Nash, A. A., York, I. A., Pohl, J., Davidson, D. J., & Donis, R. O. (2011). Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37. PLOS ONE, 6(10), Article e25333. https://doi.org/10.1371/journal.pone.0025333

The extensive world-wide morbidity and mortality caused by influenza A viruses highlights the need for new insights into the host immune response and novel treatment approaches. Cationic Host Defense Peptides (CHDP, also known as antimicrobial peptid... Read More about Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37.

The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium (2010)
Journal Article
Barlow, P. G., Beaumont, P. E., Cosseau, C., Mackellar, A., Wilkinson, T. S., Hancock, R. E. W., Haslett, C., Govan, J. R. W., Simpson, A. J., & Davidson, D. J. (2010). The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium. American Journal of Respiratory Cell and Molecular Biology, 43(6), 692-702. https://doi.org/10.1165/rcmb.2009-0250oc

Cationic host defense peptides are key, evolutionarily conserved components of the innate immune system. The human cathelicidin LL-37 is an important cationic host defense peptide up-regulated in infection and inflammation, specifically in the human... Read More about The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium.

A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice (2010)
Journal Article
Steitz, J., Barlow, P. G., Hossain, J., Kim, E., Okada, K., Kenniston, T., Rea, S., Donis, R. O., & Gambotto, A. (2010). A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice. PLOS ONE, 5(5), Article e10492. https://doi.org/10.1371/journal.pone.0010492

Background
In 2009 a new pandemic disease appeared and spread globally. The recent emergence of the pandemic influenza virus H1N1 first isolated in Mexico and USA raised concerns about vaccine availability. We here report our development of an adeno... Read More about A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice.

Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles (2010)
Journal Article
Song, J.-M., Kim, Y.-C., Barlow, P. G., Hossain, M. J., Park, K.-M., Donis, R. O., Prausnitz, M. R., Compans, R. W., & Kang, S.-M. (2010). Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles. Antiviral Research, 88(2), 244-247. https://doi.org/10.1016/j.antiviral.2010.09.001

To develop a more effective vaccination method against H5N1 virus, we investigated the immunogenicity and protective efficacy after skin vaccination using microneedles coated with influenza virus-like particles containing hemagglutinin derived from A... Read More about Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles.

NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy (2010)
Journal Article
Fox, S., Wilkinson, T. S., Wheatley, P. S., Xiao, B., Morris, R. E., Sutherland, A., Simpson, A. J., Barlow, P. G., Butler, A. R., Megson, I. L., & Rossi, A. G. (2010). NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy. Acta biomaterialia, 6(4), 1515-1521. https://doi.org/10.1016/j.actbio.2009.10.038

Nitric oxide (NO) is important for the regulation of a number of diverse biological processes, including vascular tone, neurotransmission, inflammatory cell responsiveness, defence against invading pathogens and wound healing. Transition metal exchan... Read More about NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy.