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Outputs (20)

Ferlavirus-related deaths in a collection of viperid snakes (2018)
Journal Article
Flach, E. J., Dagleish, M. P., Feltrer, Y., Gill, I. S., Marschang, R. E., Masters, N., Orós, J., Pocknell, A., Rendle, M. E., Strike, T., Tapley, B., & Wheelhouse, N. M. (2018). Ferlavirus-related deaths in a collection of viperid snakes. Journal of Zoo and Wildlife Medicine, 49(4), 983-995. https://doi.org/10.1638/2017-0223.1

Between June and October 2013 26 snakes of six viperid species kept in two adjoining rooms died (n = 16) or were euthanized on medical (1) or welfare grounds (9). Two were from the main zoo collection, but the other 24 had been imported and quarantin... Read More about Ferlavirus-related deaths in a collection of viperid snakes.

Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry (2018)
Journal Article
Dancer, S. J., & Kramer, A. (2019). Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry. Journal of Hospital Infection, 103(1), e1-e8. https://doi.org/10.1016/j.jhin.2018.12.015

Background
Now that cleaning and decontamination are recognised as integral to infection control, it is timely to examine the process in more detail. This is because cleaning practices vary widely within healthcare districts and it is likely that bo... Read More about Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry.

Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease (2018)
Journal Article
Hooper, K. M., Barlow, P. G., Henderson, P., & Stevens, C. (2019). Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 25(4), 661-671. https://doi.org/10.1093/ibd/izy380

Inflammatory Bowel Disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis, is characterised by chronic inflammation of the gastrointestinal tract. Aetiology involves a combination of genetic and environmental factors resulting in a... Read More about Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease.

Researching skills development: students as partners in this process (2018)
Journal Article
Campbell Casey, S., MacCallum, J., Robertson, L., & Strachan, L. (2018). Researching skills development: students as partners in this process. New Directions in the Teaching of Physical Sciences, 13(1), https://doi.org/10.29311/ndtps.v0i13.2881

Many employers report that newly qualified graduates lack key skills necessary for success in the workplace. Although variable, many lack general ‘transferable’ or ‘soft’ skills including communication and teamworking. Staff at Edinburgh Napier Unive... Read More about Researching skills development: students as partners in this process.

Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity (2018)
Journal Article
Ross, M. D. (2018). Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity. Current Cardiology Reviews, 14(4), 233-244. https://doi.org/10.2174/1573403X14666180726112303

The endothelium plays an important role in cardiovascular regulation, from blood flow, to platelet aggregation, immune cell infiltration and demargination. A dysfunctional endothelium leads to the onset and progression of cardiovascular disease (CVD)... Read More about Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity.

Protracted diagnosis of ACNES: a costly exercise (2018)
Journal Article
Dancer, S. J., Macpherson, S. G., & de Beaux, A. C. (2018). Protracted diagnosis of ACNES: a costly exercise. Journal of Surgical Case Reports, 2018(9), 1-3. https://doi.org/10.1093/jscr/rjy230

This case report summarizes the course of events leading to diagnosis and eventual repair of anterior cutaneous nerve entrapment syndrome (ACNES) in a 58-year-old female. The time period elapsing from initial symptoms to final operative repair was 9... Read More about Protracted diagnosis of ACNES: a costly exercise.

Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring (2018)
Journal Article
Wauters, J., Wilson, K. S., Bouts, T., Valentine, I., Vanderschueren, K., Ververs, C., Howie, A. F., Rae, M. T., Van Soom, A., Li, R., Li, D., Zhang, H., & Vanhaecke, L. (2018). Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring. PLOS ONE, 13(7), Article e0201420. https://doi.org/10.1371/journal.pone.0201420

Reproductive monitoring for captive breeding in giant pandas is based on behavioural observation and non-invasive hormone analysis. In urine, interpretation of results requires normalisation due to an animal’s changing hydration. Correction of urinar... Read More about Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring.

Beware Biofilm! Dry biofilms containing bacterial pathogens on multiple healthcare surfaces; a multicentre study (2018)
Journal Article
Ledwoch, K., Dancer, S., Otter, J., Kerr, K., Roposte, D., Rushton, L., Weiser, R., Mahenthiralingam, E., Muir, D., & Maillard, J.-Y. (2018). Beware Biofilm! Dry biofilms containing bacterial pathogens on multiple healthcare surfaces; a multicentre study. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2018.06.028

Background
Wet biofilms associated with medical devices have been widely studied and their link with healthcare-associated infections (HCAIs) is well recognized. Little attention has been paid to the presence of dry biofilms on environmental surface... Read More about Beware Biofilm! Dry biofilms containing bacterial pathogens on multiple healthcare surfaces; a multicentre study.

Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men (2018)
Journal Article
Ross, M., Ingram, L., Taylor, G., Malone, E., Simpson, R. J., West, D., & Florida-James, G. (2018). Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men. Physiological Reports, 6(12), Article e13697. https://doi.org/10.14814/phy2.13697

Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative ability. CD31+ T-cells (angiogenic T-cells; TANG) possess highly angiogenic capa... Read More about Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men.

Antiviral therapeutic approaches for human rhinovirus infections (2018)
Journal Article
Casanova, V., Sousa, F. H., Stevens, C., & Barlow, P. G. (2018). Antiviral therapeutic approaches for human rhinovirus infections. Future Virology, https://doi.org/10.2217/fvl-2018-0016

Human rhinoviruses (RV) are the primary etiological agent of the common cold. This infection can be mild and self-limiting in immunocompetent hosts, but can be associated with bronchiolitis in infants, pneumonia in the immunosuppressed, and exacerba... Read More about Antiviral therapeutic approaches for human rhinovirus infections.

Estimating excess length of stay due to healthcare-associated infections: A systematic review and meta-analysis of statistical methodology (2018)
Journal Article
Manoukian, S., Stewart, S., Dancer, S., Graves, N., Mason, H., McFarland, A., Robertson, C., & Reilly, J. (2018). Estimating excess length of stay due to healthcare-associated infections: A systematic review and meta-analysis of statistical methodology. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2018.06.003

Background
Healthcare-associated infection (HAI) affects millions of patients worldwide. HAI is associated with increased healthcare costs, owing primarily to increased hospital length of stay (LOS) but calculating these costs is complicated due to... Read More about Estimating excess length of stay due to healthcare-associated infections: A systematic review and meta-analysis of statistical methodology.

Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations (2018)
Journal Article
Kemp, S., Young, L., Ross, M., Prach, M., Hutchison, G. R., Malone, E., & Fraser, J. A. (2018). Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations. Scientific Reports, 8(1), Article 7506. https://doi.org/10.1038/s41598-018-25854-2

Neutrophil surveillance is central to nanoparticle clearance. Silver nanoparticles (AgNP) have numerous uses, however conflicting evidence exists as to their impact on neutrophils and whether they trigger damaging inflammation. Neutrophil’s importanc... Read More about Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations.

Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment (2018)
Journal Article
Boukelia, Z., Gomes, E. C., & Florida-James, G. D. (2018). Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment. Oxidative Medicine and Cellular Longevity, 2018, Article 3402143. https://doi.org/10.1155/2018/3402143

Purpose. The purpose of this study was to investigate the physiological and immunological response of highly trained runners to an intense bout of exercise performed at two different times of day, in a hot, humid environment. Methods. Using a crossov... Read More about Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment.

Is there an association between airborne and surface microbes in the critical care environment? (2018)
Journal Article
Smith, J., Adams, C., King, M., Noakes, C., Robertson, C., & Dancer, S. (2018). Is there an association between airborne and surface microbes in the critical care environment?. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2018.04.003

Background
There are few data and no accepted standards for air quality in the intensive care unit (ICU). Any relationship between airborne pathogens and hospital-acquired infection (HAI) risk in the ICU remains unknown.
Aim
First, to correlate en... Read More about Is there an association between airborne and surface microbes in the critical care environment?.

Quantifying the relative effect of environmental contamination on surgical ward MRSA incidence: An exploratory analysis (2018)
Journal Article
Lee, X. J., Pettitt, A. N., & Dancer, S. J. (2018). Quantifying the relative effect of environmental contamination on surgical ward MRSA incidence: An exploratory analysis. Infection, Disease & Health, https://doi.org/10.1016/j.idh.2018.02.005

Background: To investigate and quantify the contribution of environmental contamination towards methicillin-resistant Staphylococcus aureus (MRSA) incidence observed in a hospital ward using stochastic modelling. Methods: A non-homogeneous Poisson pr... Read More about Quantifying the relative effect of environmental contamination on surgical ward MRSA incidence: An exploratory analysis.

Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment (2018)
Journal Article
Ahmad, S. F., Brown, J. K., Campbell, L. L., Koscielniak, M., Oliver, C., Wheelhouse, N., Entrican, G., McFee, S., Wills, G. S., McClure, M. O., Horner, P. J., Gaikoumelou, S., Lee, K. F., Critchley, H. O., Duncan, W. C., & Horne, A. W. (2018). Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment. EBioMedicine, 29, 159-165. https://doi.org/10.1016/j.ebiom.2018.02.020

Tubal ectopic pregnancies are a leading cause of global maternal morbidity and mortality. Previous infection with Chlamydia trachomatis is a major risk factor for tubal embryo implantation but the biological mechanism behind this association is uncle... Read More about Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment.

How Does a Photocatalytic Antimicrobial Coating Affect Environmental Bioburden in Hospitals? (2018)
Journal Article
Reid, M., Whatley, V., Spooner, E., Nevill, A. M., Cooper, M., Ramsden, J. J., & Dancer, S. J. (2018). How Does a Photocatalytic Antimicrobial Coating Affect Environmental Bioburden in Hospitals?. Infection Control and Hospital Epidemiology, 39(4), 398-404. https://doi.org/10.1017/ice.2017.297

BACKGROUND The healthcare environment is recognized as a source for healthcare-acquired infection. Because cleaning practices are often erratic and always intermittent, we hypothesize that continuously antimicrobial surfaces offer superior control of... Read More about How Does a Photocatalytic Antimicrobial Coating Affect Environmental Bioburden in Hospitals?.

A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion (2018)
Journal Article
Staines, K. A., Lee, P. D., Pitsillides, A. A., Staines, K., Madi, K., Javaheri, B., Lee, P., & Pitsillides, A. (2018). A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion. Frontiers in Materials, 4, https://doi.org/10.3389/fmats.2017.00048

The epiphyseal growth plate is a developmental region responsible for linear bone growth, in which chondrocytes undertake a tightly regulated series of biological processes. Concomitant with the cessation of growth and sexual maturation, the human gr... Read More about A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion.