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Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status (2012)
Journal Article
Prach, M., Stone, V., & Proudfoot, L. (2012). Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status. Toxicology and Applied Pharmacology, 266(1), 19-26. https://doi.org/10.1016/j.taap.2012.10.020

Zinc oxide (ZnO) particle induced cytotoxicity was dependent on size, charge and solubility, factors which at sublethal concentrations may influence the activation of the human monocytic cell line THP1. ZnO nanoparticles (NP; average diameter 70 nm)... Read More about Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status.

Chondrogenic ATDC5 cells: An optimised model for rapid and physiological matrix mineralisation (2012)
Journal Article
Newton, P. T., Staines, K. .. . A., Spevak, L., Boskey, A. L., Teixeira, C. C., Macrae, V. E., Canfield, A. E., & Farquharson, C. (2012). Chondrogenic ATDC5 cells: An optimised model for rapid and physiological matrix mineralisation. International Journal of Molecular Medicine, 30(5), 1187-1193. https://doi.org/10.3892/ijmm.2012.1114

The development of chondrogenic cell lines has led to major advances in the understanding of how chondrocyte differentiation is regulated, and has uncovered many signalling pathways and gene regulatory mechanisms required to maintain normal function.... Read More about Chondrogenic ATDC5 cells: An optimised model for rapid and physiological matrix mineralisation.

Cartilage development and degeneration: a Wnt Wnt situation - cartilage development and degeneration: a WNT WNT situation (2012)
Journal Article
Staines, K. A., MacRae, V. E., & Farquharson, C. (2012). Cartilage development and degeneration: a Wnt Wnt situation - cartilage development and degeneration: a WNT WNT situation. Cell Biochemistry and Function, 30(8), 633-642. https://doi.org/10.1002/cbf.2852

The Wnt signaling pathway plays a crucial role in the development and homeostasis of a variety of adult tissues and, as such, is emerging as an important therapeutic target for numerous diseases. Factors involved in the Wnt pathway are expressed thro... Read More about Cartilage development and degeneration: a Wnt Wnt situation - cartilage development and degeneration: a WNT WNT situation.

The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling (2012)
Journal Article
Staines, K. A., MacRae, V. E., & Farquharson, C. (2012). The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling. Journal of Endocrinology, 214(3), 241-255. https://doi.org/10.1530/joe-12-0143

The small integrin-binding ligand N-linked glycoprotein (SIBLING) family consists of osteopontin, bone sialoprotein, dentin matrix protein 1, dentin sialophosphoprotein and matrix extracellular phosphoglycoprotein. These proteins share many structura... Read More about The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling.