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Outputs (11)

The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium (2010)
Journal Article
Barlow, P. G., Beaumont, P. E., Cosseau, C., Mackellar, A., Wilkinson, T. S., Hancock, R. E. W., Haslett, C., Govan, J. R. W., Simpson, A. J., & Davidson, D. J. (2010). The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium. American Journal of Respiratory Cell and Molecular Biology, 43(6), 692-702. https://doi.org/10.1165/rcmb.2009-0250oc

Cationic host defense peptides are key, evolutionarily conserved components of the innate immune system. The human cathelicidin LL-37 is an important cationic host defense peptide up-regulated in infection and inflammation, specifically in the human... Read More about The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium.

Alternative Assessment for a Visually Impaired Student (2010)
Digital Artefact
Garden, C., Chalmers, C., Orwat, M., & Booth, S. (2010). Alternative Assessment for a Visually Impaired Student. [http://staff.napier.ac.uk/services/dlte/LTA/resources/Pages/Details.aspx?ItemID=48&Section=CS]

Essay writing in a scientific style is considered to be a key skill for students studying Biological Sciences and Sport and Exercise science. An assessment in the core first year module “Introductory Physiology” therefore includes an essay on one of... Read More about Alternative Assessment for a Visually Impaired Student.

Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task (2010)
Journal Article
Simpson, R. J., Graham, S. M., Florida-James, G. D., Connaboy, C., Clement, R., & Jackson, A. S. (2010). Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task. Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme, 35(5), 650-656. https://doi.org/10.1139/h10-053

Identifying field measures to estimate backpack load-carriage work intensity in elite soldiers is of interest to the military. This study developed rating of perceived exertion (RPE) and heart rate models to define metabolic workload for a backpack l... Read More about Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task.

Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles (2010)
Journal Article
Song, J.-M., Kim, Y.-C., Barlow, P. G., Hossain, M. J., Park, K.-M., Donis, R. O., Prausnitz, M. R., Compans, R. W., & Kang, S.-M. (2010). Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles. Antiviral Research, 88(2), 244-247. https://doi.org/10.1016/j.antiviral.2010.09.001

To develop a more effective vaccination method against H5N1 virus, we investigated the immunogenicity and protective efficacy after skin vaccination using microneedles coated with influenza virus-like particles containing hemagglutinin derived from A... Read More about Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles.

A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice (2010)
Journal Article
Steitz, J., Barlow, P. G., Hossain, J., Kim, E., Okada, K., Kenniston, T., Rea, S., Donis, R. O., & Gambotto, A. (2010). A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice. PLOS ONE, 5(5), Article e10492. https://doi.org/10.1371/journal.pone.0010492

Background
In 2009 a new pandemic disease appeared and spread globally. The recent emergence of the pandemic influenza virus H1N1 first isolated in Mexico and USA raised concerns about vaccine availability. We here report our development of an adeno... Read More about A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice.

NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy (2010)
Journal Article
Fox, S., Wilkinson, T. S., Wheatley, P. S., Xiao, B., Morris, R. E., Sutherland, A., Simpson, A. J., Barlow, P. G., Butler, A. R., Megson, I. L., & Rossi, A. G. (2010). NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy. Acta biomaterialia, 6(4), 1515-1521. https://doi.org/10.1016/j.actbio.2009.10.038

Nitric oxide (NO) is important for the regulation of a number of diverse biological processes, including vascular tone, neurotransmission, inflammatory cell responsiveness, defence against invading pathogens and wound healing. Transition metal exchan... Read More about NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy.

Androgen action in the masculinization programming window and development of male reproductive organs (2010)
Journal Article
MacLeod, D. J., Sharpe, R. M., Welsh, M., Fisken, M., Scott, H. M., Hutchison, G. R., Drake, A. J., & van den Driesche, S. (2010). Androgen action in the masculinization programming window and development of male reproductive organs. International Journal of Andrology, 33(2), 279-287. https://doi.org/10.1111/j.1365-2605.2009.01005.x

We have shown previously that deficient androgen action within a masculinization programming window (MPW; e15.5–e18.5 in rats) is important in the origin of male reproductive disorders and in programming male reproductive organ size, but that androge... Read More about Androgen action in the masculinization programming window and development of male reproductive organs.

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity (2010)
Journal Article
Johnston, H. J., Hutchison, G., Christensen, F. M., Peters, S., Hankin, S., & Stone, V. (2010). A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity. Critical Reviews in Toxicology, 40(4), 328-346. https://doi.org/10.3109/10408440903453074

This review is concerned with evaluating the toxicity associated with human exposure to silver and gold nanoparticles (NPs), due to the relative abundance of toxicity data available for these particles, when compared to other metal particulates. This... Read More about A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity.

A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics (2010)
Journal Article
Johnston, H. J., Hutchison, G. R., Christensen, F. M., Peters, S., Hankin, S., Aschberger, K., & Stone, V. (2010). A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics. Nanotoxicology, 4(2), 207-246. https://doi.org/10.3109/17435390903569639

This critical review of the available human health safety data, relating to carbon nanotubes (CNTs), was conducted in order to assess the risks associated with CNT exposure. Determining the toxicity related to CNT exploitation is of great relevance a... Read More about A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics.

Regulation of capsule expression (2010)
Book Chapter
Taylor, C., & Roberts, I. S. (2010). Regulation of capsule expression. In . M. Wilson (Ed.), Bacterial Adhesion to Host Tissues: Mechanisms and Consequences (115-138). Cambridge University Press

No abstract available.