Outputs (6)

Investigating the role of cell fate regulator ASCL1 in driving and maintaining lethal neuroendocrine castrate resistant prostate cancer (2022)
Presentation / Conference Contribution
Bruce, I., Pang, L., Poole, A., & Fraser, J. (2022, November). Investigating the role of cell fate regulator ASCL1 in driving and maintaining lethal neuroendocrine castrate resistant prostate cancer. Poster presented at Society for Endocrinology BES 2022, Harrogate

Neuroendocrine castrate resistant prostate cancer (NE-CRPC) is a lethal CRPC subtype that arises as prostate cancer cells transdifferentiate to neuroendocrine cells, evading the potent selective pressure of androgen deprivation therapies (ADT). Curre... Read More about Investigating the role of cell fate regulator ASCL1 in driving and maintaining lethal neuroendocrine castrate resistant prostate cancer.

Hardware Design for Autonomous Robot Evolution (2020)
Presentation / Conference Contribution
Hale, M. F., Angus, M., Buchanan, E., Li, W., Woolley, R., Le Goff, L. K., De Carlo, M., Timmis, J., Winfield, A. F., Hart, E., Eiben, A. E., & Tyrrell, A. M. (2020, December). Hardware Design for Autonomous Robot Evolution. Presented at International Conference on Evolvable Hardware, Canberra Australia

The long term goal of the Autonomous Robot Evolution (ARE) project is to create populations of physical robots, in which both the controllers and body plans are evolved. The transition for evolutionary designs from purely simulation environments into... Read More about Hardware Design for Autonomous Robot Evolution.

Exploring male identity in non-professional carers of someone with cancer: preliminary analysis (2018)
Presentation / Conference Contribution
Young, J., Snowden, A., Stenhouse, R., & Kyle, R. (2018, March). Exploring male identity in non-professional carers of someone with cancer: preliminary analysis. Poster presented at British Psych-Oncology Society Annual Conference, Southampton

Background
Across the world the majority of home‐based care for ill family members is carried out by women. Consequently, research in this field has predominately focused on female carers, meaning less is known about the male carer experience. My s... Read More about Exploring male identity in non-professional carers of someone with cancer: preliminary analysis.

Holistic Needs Assessment in Brain Cancer Patients: A Systematic Review of Available Tools (2017)
Presentation / Conference Contribution
Afseth, J., Neubeck, L., Karatzias, T., & Grant, R. (2017, June). Holistic Needs Assessment in Brain Cancer Patients: A Systematic Review of Available Tools. Poster presented at British Neuro Oncology Conference

BACKGROUND: A diagnosis of brain cancer affects nearly 10 000 adults per year in the United Kingdom and has a devastating impact. This is due to the poor prognosis as well as a significant symptom burden, which often includes neurocognitive deficits.... Read More about Holistic Needs Assessment in Brain Cancer Patients: A Systematic Review of Available Tools.

Investigating the molecular mechanisms driving neuroendocrine differentiation in androgen deprived prostate cancer cells (2016)
Presentation / Conference Contribution
Sutton, J., Hutchison, G., Fraser, J., & Poole, A. (2016, November). Investigating the molecular mechanisms driving neuroendocrine differentiation in androgen deprived prostate cancer cells. Presented at National Cancer Research Institute Conference, Liverpool, UK

Background: Neuroendocrine differentiation is commonplace in prostate tumors treated with androgen deprivation therapy and is associated with castrate-resistant disease progression and poor prognosis. The molecular mechanisms driving neuroendocrine d... Read More about Investigating the molecular mechanisms driving neuroendocrine differentiation in androgen deprived prostate cancer cells.

In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome (2014)
Presentation / Conference Contribution
Girardi, G., Fraser, J., Bertolaccini, M. L., Lennen, R., Vontell, R., & Hutchison, G. (2014, December). In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome

Objectives: To use MRI-based methods to non invasively detect placental insufficiency and predict fetal outcomes in obstetric antiphospholipid syndrome (APS)
Methods and result: A) Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles conjug... Read More about In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome.