Outputs (3)

Androgen-dependent Sertoli cell proliferation as a target for endocrine disruptors relevant to human male reproductive health (2006)
Presentation / Conference Contribution
Scott, H., Hallmark, N., Saunders, P., Verhoeven, G., De Gendt, K., Hutchison, G., & Sharpe, R. Androgen-dependent Sertoli cell proliferation as a target for endocrine disruptors relevant to human male reproductive health. Presented at 8th European Congress of Endocrinology incorporating the British Endocrine Societies, Glasgow, UK

Smoking by women during pregnancy can result in a 30–48% reduction in sperm count and testis size in the exposed offspring in adulthood, probably because of a decrease in the number of Sertoli cells. Until recently Sertoli cell proliferation was thou... Read More about Androgen-dependent Sertoli cell proliferation as a target for endocrine disruptors relevant to human male reproductive health.

Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary. (2006)
Journal Article
Lea, R. G., Andrade, L. P., Rae, M. T., Hannah, L. T., Kyle, C. E., Murray, J. F., Rhind, S. M., & Miller, D. W. (2006). Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary. Reproduction, 131, 113-124. https://doi.org/10.1530/rep.1.00844

This study aimed to determine whether reduced fetal ovary folliculogenesis in ewes undernourished during early/midpregnancy is associated with altered ovarian cell proliferation and/or the expression of apoptosis-regulating genes. Groups of ewes (n =... Read More about Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary..

cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival (2006)
Journal Article
Gubbay, O., Rae, M. T., McNeilly, A. S., Donadeu, F. X., Zeleznik, A. J., & Hillier, S. G. (2006). cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival. Journal of Endocrinology, 191(1), 275-285. https://doi.org/10.1677/joe.1.06928

cAMP response-element binding (CREB) transcription factors transduce cell survival responses to peptide hormones and growth factors in normal tissues and mutant CREB proteins are implicated in tumorigenesis. Ovarian cancer most frequently arises from... Read More about cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival.