Outputs (51)

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity (2010)
Journal Article
Johnston, H. J., Hutchison, G., Christensen, F. M., Peters, S., Hankin, S., & Stone, V. (2010). A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity. Critical Reviews in Toxicology, 40(4), 328-346. https://doi.org/10.3109/10408440903453074

This review is concerned with evaluating the toxicity associated with human exposure to silver and gold nanoparticles (NPs), due to the relative abundance of toxicity data available for these particles, when compared to other metal particulates. This... Read More about A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity.

A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics (2010)
Journal Article
Johnston, H. J., Hutchison, G. R., Christensen, F. M., Peters, S., Hankin, S., Aschberger, K., & Stone, V. (2010). A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics. Nanotoxicology, 4(2), 207-246. https://doi.org/10.3109/17435390903569639

This critical review of the available human health safety data, relating to carbon nanotubes (CNTs), was conducted in order to assess the risks associated with CNT exposure. Determining the toxicity related to CNT exploitation is of great relevance a... Read More about A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics.

Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics (2009)
Journal Article
Johnston, H. J., Hutchison, G. R., Christensen, F. M., Peters, S., Hankin, S., & Stone, V. (2009). Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics. Particle and fibre toxicology, 6(1), 33. https://doi.org/10.1186/1743-8977-6-33

This review focuses on outlining the toxicity of titanium dioxide (TiO₂) particulates in vitro and in vivo, in order to understand their ability to detrimentally impact on human health. Evaluating the hazards associated with TiO₂ particles is vital a... Read More about Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics.

Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development (2009)
Journal Article
Drake, A. J., van den Driesche, S., Scott, H. M., Hutchison, G. R., Seckl, J. R., & Sharpe, R. M. (2009). Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development. Endocrinology, 150(11), 5055-5064. https://doi.org/10.1210/en.2009-0700

Common male reproductive abnormalities including cryptorchidism, hypospadias, and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal testis dysfunction during a critical developmental period involving reduced a... Read More about Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development.

The Biological Mechanisms and Physicochemical Characteristics Responsible for Driving Fullerene Toxicity (2009)
Journal Article
Johnston, H. J., Hutchison, G. R., Christensen, F. M., Aschberger, K., & Stone, V. (2010). The Biological Mechanisms and Physicochemical Characteristics Responsible for Driving Fullerene Toxicity. Toxicological Sciences, 114(2), 162-182. https://doi.org/10.1093/toxsci/kfp265

This review provides a comprehensive critical review of the available literature purporting to assess the toxicity of carbon fullerenes. This is required as prior to the widespread utilization and production of fullerenes, it is necessary to consider... Read More about The Biological Mechanisms and Physicochemical Characteristics Responsible for Driving Fullerene Toxicity.

The effect of suspension bath composition on the composition, topography and structure of electrolessly deposited composite four-component Ni–W–P–ZrO2 coatings (2008)
Journal Article
Szczygieł, B., & Turkiewicz, A. (2008). The effect of suspension bath composition on the composition, topography and structure of electrolessly deposited composite four-component Ni–W–P–ZrO2 coatings. Applied Surface Science, 254(22), 7410-7416. https://doi.org/10.1016/j.apsusc.2008.05.342

Composite four-component Ni–W–P–ZrO2 coatings were electrolessly deposited from a bath with different concentrations of aminoacetic acid (glycine—the complexing agent), sodium tungstate(VI) and zirconium(IV) oxide at different pH values. Concentratio... Read More about The effect of suspension bath composition on the composition, topography and structure of electrolessly deposited composite four-component Ni–W–P–ZrO2 coatings.

Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1 (2007)
Journal Article
Hutchison, G. R., Scott, H. M., Walker, M., McKinnell, C., Ferrara, D., Mahood, I. K., & Sharpe, R. M. (2008). Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1. Biology of Reproduction, 78(2), 352-360. https://doi.org/10.1095/biolreprod.107.064006

Pregnancy exposure to di(n-butyl) phthalate (DBP) in rats induces a testicular dysgenesislike syndrome (TDS) in male offspring. Earlier studies suggested altered Sertoli cell development/maturation may result, especially in testes that become cryptor... Read More about Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1.

The origins and time of appearance of focal testicular dysgenesis in an animal model of testicular dysgenesis syndrome: evidence for delayed testis development? (2007)
Journal Article
Hutchison, G. R., Sharpe, R. M., Mahood, I. K., Jobling, M., Walker, M., McKinnell, C., Mason, J. I., & Scott, H. M. (2008). The origins and time of appearance of focal testicular dysgenesis in an animal model of testicular dysgenesis syndrome: evidence for delayed testis development?. International Journal of Andrology, 31(2), 103-111. https://doi.org/10.1111/j.1365-2605.2007.00816.x

A testicular dysgenesis-like syndrome is induced in rats by fetal exposure todi(n-butyl) phthalate (DBP). A key feature of this is the formation of focal dys-genetic areas comprising malformed seminiferous cords⁄tubules and intratubu-lar Leydig cells... Read More about The origins and time of appearance of focal testicular dysgenesis in an animal model of testicular dysgenesis syndrome: evidence for delayed testis development?.

Consequences for the male fetus: Time windows of testosterone action and susceptibility to disorders of ‘masculinisation’ (2007)
Journal Article
Sharpe, R. M., Scott, H. M., Hutchison, G., Walker, M., McKinnell, C., Saunders, P., & Welsh, M. (2007). Consequences for the male fetus: Time windows of testosterone action and susceptibility to disorders of ‘masculinisation’. Toxicology, 240(3), 144-145. https://doi.org/10.1016/j.tox.2007.06.027

Conference abstract in Proceedings of the Annual Congress of The British Toxicology Society.

Flexural behaviour of Rectangular Hollow Sections with circular side wall openings. (2001)
Presentation / Conference Contribution
Ridley-Ellis, D. J., Owen, J. S., & Davies, G. (2001, April). Flexural behaviour of Rectangular Hollow Sections with circular side wall openings. Presented at Tubular Structures - International Symposium

The influence of circular web openings on the flexura behaviour of Rectangular Hollow Sections is introduced. The results of full-scale laboratory tests in three and four-point bending and the development of analytical finite element models to predi... Read More about Flexural behaviour of Rectangular Hollow Sections with circular side wall openings..

A higher-order finite element framework for hyper-visco-elastodynamics of soft multifuctional composites
Presentation / Conference Contribution
Kadapa, C., & Hossain, M. (2024, April). A higher-order finite element framework for hyper-visco-elastodynamics of soft multifuctional composites. Paper presented at UK Association for Computational Mechanics Conference 2024, Durham, UK

Smart multifunctional polymeric composites such as electroactive polymers, magnetoactive polymers and active hydrogels find numerous applications in soft robotics, energy harvesting, flexible electronic devices, tactile sensors, precision drug delive... Read More about A higher-order finite element framework for hyper-visco-elastodynamics of soft multifuctional composites.