All Outputs (3)

Exercise protection of vascular endothelial cells against breast cancer chemotherapy toxicity: Evidence from in vitro serological studies (2022)
Thesis
Mclaughlin, M. Exercise protection of vascular endothelial cells against breast cancer chemotherapy toxicity: Evidence from in vitro serological studies. (Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/2951034

5-fluorouracil, epirubicin, cyclophosphamide, and docetaxel is an effective chemotherapy regimen for early-stage breast cancer (BC). However, these drugs associate with a 5% incidence of heart failure (HF). To attenuate the cardiovascular toxicity of... Read More about Exercise protection of vascular endothelial cells against breast cancer chemotherapy toxicity: Evidence from in vitro serological studies.

Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic (2021)
Journal Article
Mclaughlin, M., Florida-James, G., & Ross, M. (2021). Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic. Vascular Biology, 3(1), R106-R120. https://doi.org/10.1530/VB-21-0013

Breast cancer chemotherapy, although very potent against tumour tissue, results in significant cardiovascular toxicity. The focus of research in this area has been predominantly towards cardiotoxicity. There is limited evidence detailing the impact o... Read More about Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic.

Case Report of Exercise to Attenuate Side Effects of Treatment for Pancreatic Cancer (2019)
Journal Article
Mclaughlin, M., Christie, A., & Campbell, A. (2019). Case Report of Exercise to Attenuate Side Effects of Treatment for Pancreatic Cancer. Case Reports in Oncology, 12(3), 845-854. https://doi.org/10.1159/000503815

Treatments for pancreatic cancer can have debilitating side effects including fatigue, weight loss, and cardiac toxicity, resulting in functional loss and psychological distress. Exercise has been proposed as a therapy to counteract physical and psyc... Read More about Case Report of Exercise to Attenuate Side Effects of Treatment for Pancreatic Cancer.