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All Outputs (2)

Molecular mechanisms driving prostate cancer neuroendocrine differentiation (2019)
Thesis
Sutton, J. E. Molecular mechanisms driving prostate cancer neuroendocrine differentiation. (Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/2414975

Annually, 11,500 men in the UK die of prostate cancer (PCa). PCa tumours are initially dependent upon androgen receptor (AR) signalling and androgen deprivation therapy (ADT) is highly effective in restricting tumour growth. However, ADT resistance a... Read More about Molecular mechanisms driving prostate cancer neuroendocrine differentiation.

Investigating the molecular mechanisms driving neuroendocrine differentiation in androgen deprived prostate cancer cells (2016)
Conference Proceeding
Sutton, J., Hutchison, G., Fraser, J., & Poole, A. (2016). Investigating the molecular mechanisms driving neuroendocrine differentiation in androgen deprived prostate cancer cells

Background: Neuroendocrine differentiation is commonplace in prostate tumors treated with androgen deprivation therapy and is associated with castrate-resistant disease progression and poor prognosis. The molecular mechanisms driving neuroendocrine d... Read More about Investigating the molecular mechanisms driving neuroendocrine differentiation in androgen deprived prostate cancer cells.