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Safety and Feasibility of a 16-Week Progressive Exercise Intervention in Treatment Naïve Chronic Lymphocytic Leukaemia (2023)
Journal Article
Brown, F. F., Oliver, R., Causer, A. J., Collier-Bain, H. D., Emery, A., Eddy, R., …Campbell, J. P. (2023). Safety and Feasibility of a 16-Week Progressive Exercise Intervention in Treatment Naïve Chronic Lymphocytic Leukaemia. Blood, 142(suppl 1), 6533. https://doi.org/10.1182/blood-2023-186956

A growing body of evidence from preclinical and human epidemiology studies of multiple cancer types indicate that physical activity can delay or avert the outgrowth of cancer, in a mechanistic process that may involve exercise-indu... Read More about Safety and Feasibility of a 16-Week Progressive Exercise Intervention in Treatment Naïve Chronic Lymphocytic Leukaemia.

Harnessing the immunomodulatory effects of exercise to enhance the efficacy of monoclonal antibody therapies against B-cell haematological cancers: a narrative review (2023)
Journal Article
Collier-Bain, H. D., Brown, F. F., Causer, A. J., Emery, A., Oliver, R., Moore, S., …Campbell, J. P. (2023). Harnessing the immunomodulatory effects of exercise to enhance the efficacy of monoclonal antibody therapies against B-cell haematological cancers: a narrative review. Frontiers in Oncology, 13, Article 1244090. https://doi.org/10.3389/fonc.2023.1244090

Therapeutic monoclonal antibodies (mAbs) are standard care for many B-cell haematological cancers. The modes of action for these mAbs include: induction of cancer cell lysis by activating Fcγ-receptors on innate immune cells; opsonising target cells... Read More about Harnessing the immunomodulatory effects of exercise to enhance the efficacy of monoclonal antibody therapies against B-cell haematological cancers: a narrative review.

Patient–clinician dynamics in remote consultations: a qualitative study of cardiology and rheumatology outpatient clinics in the UK (2023)
Journal Article
Grey, E., Brown, F., Smith, P., Springett, D., Augustine, D., Sengupta, R., …Gillison, F. (2023). Patient–clinician dynamics in remote consultations: a qualitative study of cardiology and rheumatology outpatient clinics in the UK. BMJ Open, 13(5), Article e070923. https://doi.org/10.1136/bmjopen-2022-070923

Objective: Explore the experiences of patients and clinicians in rheumatology and cardiology outpatient clinics during the first year of the COVID-19 pandemic, focusing on the impact of remote consultations on interpersonal dynamics. Design: Quali... Read More about Patient–clinician dynamics in remote consultations: a qualitative study of cardiology and rheumatology outpatient clinics in the UK.

“A disembodied voice over the telephone”: a qualitative study of healthcare practitioners’ experiences in geriatric medicine (2023)
Journal Article
Brown, F., Sanders, I., Watkins, R., Grey, E., Smith, P., Springett, D., …Gillison, F. (2023). “A disembodied voice over the telephone”: a qualitative study of healthcare practitioners’ experiences in geriatric medicine. BMC Geriatrics, 23, Article 270. https://doi.org/10.1186/s12877-023-03909-y

Objectives: This study explored the experience of delivering care remotely among practitioners in a UK geriatric medicine clinic. Methods: Nine semi-structured interviews were conducted with consultants (n = 5), nurses (n = 2), a speech and langua... Read More about “A disembodied voice over the telephone”: a qualitative study of healthcare practitioners’ experiences in geriatric medicine.

The effects of exercise on complement system proteins in humans: a systematic scoping review (2022)
Journal Article
Rothschild-Rodriguez, D., Causer, A. J., Brown, F. F., Collier-Bain, H. D., Moore, S., Murray, J., …Campbell, J. P. (2022). The effects of exercise on complement system proteins in humans: a systematic scoping review. Exercise Immunology Review, 28, 58-92

Background: The complement system is comprised of the classical , lectin and alternative pathways that result in the formation of: pro-inflammatory anaphylatoxins; opsonins that label cells for phagocytic removal; and, a membrane attack complex that... Read More about The effects of exercise on complement system proteins in humans: a systematic scoping review.

‘You’re kind of left to your own devices’: a qualitative focus group study of patients with breast, prostate or blood cancer at a hospital in the South West of England, exploring their engagement with exercise and physical activity during cancer treatment and in the months following standard care (2022)
Journal Article
Smith, S. K., Wiltshire, G., Brown, F. F., Dhillon, H., Osborn, M., Wexler, S., …Turner, J. E. (2022). ‘You’re kind of left to your own devices’: a qualitative focus group study of patients with breast, prostate or blood cancer at a hospital in the South West of England, exploring their engagement with exercise and physical activity during cancer treatment and in the months following standard care. BMJ Open, 12(3), Article e056132. https://doi.org/10.1136/bmjopen-2021-056132

Objectives: The aim of this study was to explore the experiences of patients with breast, prostate or blood cancer, regarding their (1) engagement with exercise and physical activity during treatment and in the months following standard care, and (2)... Read More about ‘You’re kind of left to your own devices’: a qualitative focus group study of patients with breast, prostate or blood cancer at a hospital in the South West of England, exploring their engagement with exercise and physical activity during cancer treatment and in the months following standard care.

The experiences of cancer patients within the material hospital environment: Three ways that materiality is affective (2020)
Journal Article
Wiltshire, G., Pullen, E., Brown, F. F., Osborn, M., Wexler, S., Beresford, M., …Turner, J. E. (2020). The experiences of cancer patients within the material hospital environment: Three ways that materiality is affective. Social Science and Medicine, 264, Article 113402. https://doi.org/10.1016/j.socscimed.2020.113402

Improving the patient experience is widely recognised as an important goal in the delivery of high-quality healthcare. This study contributes to this goal with a particular focus on the role of the material hospital environment for patients being tre... Read More about The experiences of cancer patients within the material hospital environment: Three ways that materiality is affective.

Acute aerobic exercise induces a preferential mobilisation of plasmacytoid dendritic cells into the peripheral blood in man (2018)
Journal Article
Brown, F. F., Campbell, J. P., Wadley, A. J., Fisher, J. P., Aldred, S., & Turner, J. E. (2018). Acute aerobic exercise induces a preferential mobilisation of plasmacytoid dendritic cells into the peripheral blood in man. Physiology and Behavior, 194, 191-198. https://doi.org/10.1016/j.physbeh.2018.05.012

Dendritic cells (DCs) are important sentinel cells of the immune system responsible for presenting antigen to T cells. Exercise is known to cause an acute and transient increase in the frequency of DCs in the bloodstream in humans, yet there are cont... Read More about Acute aerobic exercise induces a preferential mobilisation of plasmacytoid dendritic cells into the peripheral blood in man.

n-3 Fatty Acid Supplementation During 4 Weeks of Training Leads to Improved Anaerobic Endurance Capacity, but not Maximal Strength, Speed, or Power in Soccer Players (2017)
Journal Article
Gravina, L., Brown, F. F., Alexander, L., Dick, J., Bell, G., Witard, O. C., & Galloway, S. D. (2017). n-3 Fatty Acid Supplementation During 4 Weeks of Training Leads to Improved Anaerobic Endurance Capacity, but not Maximal Strength, Speed, or Power in Soccer Players. International Journal of Sport Nutrition and Exercise Metabolism, 27(4), 305-313. https://doi.org/10.1123/ijsnem.2016-0325

Omega-3 fatty acid (n-3 FA) supplementation could promote adaptation to soccer-specific training. We examined the impact of a 4-week period of n-3 FA supplementation during training on adaptations in 1RM knee extensor strength, 20-m sprint speed, ver... Read More about n-3 Fatty Acid Supplementation During 4 Weeks of Training Leads to Improved Anaerobic Endurance Capacity, but not Maximal Strength, Speed, or Power in Soccer Players.

T-lymphocyte populations following a period of high volume training in female soccer players (2015)
Journal Article
Brown, F., Bigley, A., Ross, J., LaVoy, E., Simpson, R., & Galloway, S. (2015). T-lymphocyte populations following a period of high volume training in female soccer players. Physiology and Behavior, 152(Part A), 175-181. https://doi.org/10.1016/j.physbeh.2015.09.027

Purpose To investigate the T-lymphocyte response to a period of increased training volume in trained females compared to habitual activity in female controls. Methods Thirteen trained female (19.8 ± 1.9 yrs) soccer players were monitored during... Read More about T-lymphocyte populations following a period of high volume training in female soccer players.

Training status and sex influence on senescent T-lymphocyte redistribution in response to acute maximal exercise (2013)
Journal Article
Brown, F. F., Bigley, A. B., Sherry, C., Neal, C. M., Witard, O. C., Simpson, R. J., & Galloway, S. D. (2014). Training status and sex influence on senescent T-lymphocyte redistribution in response to acute maximal exercise. Brain, Behavior, and Immunity, 39, 152-159. https://doi.org/10.1016/j.bbi.2013.10.031

Purpose Investigate training status and sex effects on the redistribution of senescent and naïve T-lymphocytes following acute exercise. Methods Sixteen (8 male, 8 female) trained (18.3 ± 1.7 yr) soccer players (Tr) and sixteen (8 male, 8 female... Read More about Training status and sex influence on senescent T-lymphocyte redistribution in response to acute maximal exercise.