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All Outputs (12)

Validity and Responsiveness of the Generic Health-Related Quality of Life Instrument (VetMetrica™) in Cats With Osteoarthritis. Comparison of Vet and Owner Impressions of Quality of Life Impact (2021)
Journal Article
Scott, E. M., Davies, V., Nolan, A. M., Noble, C. E., Dowgray, N. J., German, A. J., …Reid, J. (2021). Validity and Responsiveness of the Generic Health-Related Quality of Life Instrument (VetMetrica™) in Cats With Osteoarthritis. Comparison of Vet and Owner Impressions of Quality of Life Impact. Frontiers in Veterinary Science, 8, Article 733812. https://doi.org/10.3389/fvets.2021.733812

Validity is not an inherent property of a measurement scale and so evidence for validity relating to its use for particular purposes, with defined populations and in specified contexts must be accumulated. We have published the development of a web-b... Read More about Validity and Responsiveness of the Generic Health-Related Quality of Life Instrument (VetMetrica™) in Cats With Osteoarthritis. Comparison of Vet and Owner Impressions of Quality of Life Impact.

Effect of Age, Breed, and Sex on the Health-Related Quality of Life of Owner Assessed Healthy Dogs (2021)
Journal Article
Rodger, S., Scott, E. M., Nolan, A., Wright, A. K., & Reid, J. (2021). Effect of Age, Breed, and Sex on the Health-Related Quality of Life of Owner Assessed Healthy Dogs. Frontiers in Veterinary Science, 8, Article 603139. https://doi.org/10.3389/fvets.2021.603139

Using an app, this exploratory study generated information on HRQL in a large cohort of dogs deemed healthy according to the owner. It forms the basis for further studies investigating the natural history of HRQL of dogs to inform the interpretation... Read More about Effect of Age, Breed, and Sex on the Health-Related Quality of Life of Owner Assessed Healthy Dogs.

Development of a behaviour-based measurement tool with defined intervention level for assessing acute pain in cats (2014)
Journal Article
Calvo, G., Holden, E., Reid, J., Scott, E. M., Firth, A., Bell, A., …Nolan, A. M. (2014). Development of a behaviour-based measurement tool with defined intervention level for assessing acute pain in cats. Journal of Small Animal Practice, 55(12), 622-629. https://doi.org/10.1111/jsap.12280

OBJECTIVES: To develop a Composite Measure Pain Scale - Feline (CMPS-F) tool to assess acute pain in cats and derive an intervention score. METHODS: To develop the prototype CMPS-F, words describing painful cats were collected, grouped into b... Read More about Development of a behaviour-based measurement tool with defined intervention level for assessing acute pain in cats.

Evaluation of facial expression in acute pain in cats (2014)
Journal Article
Holden, E., Calvo, G., Collins, M., Bell, A., Reid, J., Scott, E. M., & Nolan, A. M. (2014). Evaluation of facial expression in acute pain in cats. Journal of Small Animal Practice, 55, 615-621. https://doi.org/10.1111/jsap.12283

OBJECTIVES To describe the development of a facial expression tool differentiating pain-free cats from those in acute pain. METHODS Observers shown facial images from painful and pain-free cats were asked to identify if they were in pain or not. F... Read More about Evaluation of facial expression in acute pain in cats.

Development, validation and reliability of a web-based questionnaire to measure health-related quality of life in dogs (2013)
Journal Article
Reid, J., Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. M. (2013). Development, validation and reliability of a web-based questionnaire to measure health-related quality of life in dogs. Journal of Small Animal Practice, 54(5), 227-233. doi:10.1111/jsap.12059

Objectives To describe the development, preliminary validation and reliability testing of a shortened web-based form of GUVQuest, a structured questionnaire to measure health-related quality of life in dogs. Methods The original 109 items were... Read More about Development, validation and reliability of a web-based questionnaire to measure health-related quality of life in dogs.

Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep (2011)
Journal Article
Dolan, S., Gunn, M. D., Crossan, C., & Nolan, A. M. (2011). Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep. Behavioural Pharmacology, 22, 582-588. https://doi.org/10.1097/FBP.0b013e3283478802

This study set out to characterize the contribution of group III metabotropic glutamate receptor 7 activation to nociceptive behaviour and mechanical hypersensitivity in a novel formalin test in sheep. The mGlu receptor 7 allosteric agonist, N,N′-dib... Read More about Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep.

Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia (2011)
Journal Article
Dolan, S., Hastie, P. G. R., Crossan, C., & Nolan, A. M. (2011). Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia. Molecular Pain, 7, 91. https://doi.org/10.1186/1744-8069-7-91

Background This study characterised the effects of persistent peripheral inflammation of the foot on pain and spinal cord expression of cyclooxygenase-1 and -2 (COX-1 and COX-2) and early growth response gene 1 (Egr-1), known markers of neuronal p... Read More about Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia.

Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1) (2011)
Journal Article
Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. M. (2011). Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1). Animal Welfare, 20(4), 535=548

Health-related quality of life (HRQL) was defined for farmed animals and identified as an appropriate focus of integrative welfare measurement for farmed pigs that embraces measurement of positive welfare. The instrument for HRQL measurement was de... Read More about Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1).

Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2) (2011)
Journal Article
Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. (2011). Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2). Animal Welfare, 20(4), 549-558

The development of a novel structured questionnaire instrument to measure health-related quality of life (HRQL) in individual farmed pigs was described previously (companion paper). The instrument embraces the measurement of positive welfare, and was... Read More about Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2).

Quality of life is reduced in obese dogs but improves after successful weight loss (2011)
Journal Article
German, A. J., Holden, S. L., Wiseman-Orr, M. L., Reid, J., Nolan, A. M., Biourge, V., …Scott, E. M. (2012). Quality of life is reduced in obese dogs but improves after successful weight loss. Veterinary Journal, 192(3), 428-434. https://doi.org/10.1016/j.tvjl.2011.09.015

Obesity is thought to affect quality of life, but limited objective data exist to support this supposition. The current study aim was to use a questionnaire to determine health-related quality of life (HRQOL) both before and after weight loss, in obe... Read More about Quality of life is reduced in obese dogs but improves after successful weight loss.

The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs (2011)
Journal Article
Sandercock, D. A., Gibson, I. F., Rutherford, K. M. D., Donald, R. D., Lawrence, A. B., Brash, H. M., …Nolan, A. M. (2011). The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs. Physiology and Behavior, 104(5), 728-737. https://doi.org/10.1016/j.physbeh.2011.07.018

The consequences of tail-docking (at 2–4 days) and prenatal stress (maternal social stress during the 2nd third of pregnancy) on baseline nociceptive thresholds and responses to acute inflammatory challenge were investigated in juvenile pigs in two s... Read More about The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs.