All Outputs (4)

Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary. (2006)
Journal Article
Lea, R. G., Andrade, L. P., Rae, M. T., Hannah, L. T., Kyle, C. E., Murray, J. F., …Miller, D. W. (2006). Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary. Reproduction, 131, 113-124. https://doi.org/10.1530/rep.1.00844

This study aimed to determine whether reduced fetal ovary folliculogenesis in ewes undernourished during early/midpregnancy is associated with altered ovarian cell proliferation and/or the expression of apoptosis-regulating genes. Groups of ewes (n =... Read More about Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary..

Oestrogen formation and connective tissue growth factor expression in rat granulosa cells (2006)
Journal Article
Harlow, C. R., Bradshaw, A. C., Rae, M. T., Shearer, K. D., & Hillier, S. G. (2007). Oestrogen formation and connective tissue growth factor expression in rat granulosa cells. Journal of Endocrinology, 192(1), 41-52. https://doi.org/10.1677/joe.1.06689

Ovarian follicular development involves continual remodelling of the extracellular matrix (ECM) forming the basement membrane and intercellular framework that support granulosa cell (GC) growth and differentiation. Insight into the molecular regulati... Read More about Oestrogen formation and connective tissue growth factor expression in rat granulosa cells.

Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep (2006)
Journal Article
Hyatt, M. A., Gopalakrishnan, G. S., Bispham, J., Gentili, S., McMillen, I. C., Rhind, S. M., Rae, M. T., Kyle, C. E., Brooks, A. N., Jones, C., Budge, H., Walker, D., Stephenson, T., & Symonds, M. E. (2007). Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep. Journal of Endocrinology, 192(1), 87-97. https://doi.org/10.1677/joe.1.06801

The liver is a major metabolic and endocrine organ of critical importance in the regulation of growth and metabolism. Its function is determined by a complex interaction of nutritionally regulated counter-regulatory hormones. The extent to which hepa... Read More about Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep.

cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival (2006)
Journal Article
Gubbay, O., Rae, M. T., McNeilly, A. S., Donadeu, F. X., Zeleznik, A. J., & Hillier, S. G. (2006). cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival. Journal of Endocrinology, 191(1), 275-285. https://doi.org/10.1677/joe.1.06928

cAMP response-element binding (CREB) transcription factors transduce cell survival responses to peptide hormones and growth factors in normal tissues and mutant CREB proteins are implicated in tumorigenesis. Ovarian cancer most frequently arises from... Read More about cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival.