All Outputs (2)

Exosomes as mediators of cell-to-cell communication in prostate cancer (2021)
Thesis
Bruce, I. Exosomes as mediators of cell-to-cell communication in prostate cancer. (Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/2803794

Prostate cancer (PCa) is dependent on androgens for growth. Androgen deprivation therapy (ADT) curtails PCa progression, however this powerful selective pressure leads to aggressive, castrate resistant PCa. One castrate resistant prostate cancer subt... Read More about Exosomes as mediators of cell-to-cell communication in prostate cancer.

hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen (2019)
Journal Article
Fraser, J. A., Sutton, J. E., Tazayoni, S., Bruce, I., & Poole, A. V. (2019). hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen. Scientific Reports, 9, Article 19076 (2019). https://doi.org/10.1038/s41598-019-55665-y

Neuroendocrine prostate cancer (NEPC) is thought to arise as prostate adenocarcinoma cells transdifferentiate into neuroendocrine (NE) cells to escape potent anti-androgen therapies however, the exact molecular events accompanying NE transdifferentia... Read More about hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen.