Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A rapid test for enteric coating thickness and integrity of controlled release pellet formulations
(2018)
Journal Article
Alfarsi, A., Dillon, A., McSweeney, S., Krüse, J., Griffin, B., Devine, K., Sherry, P., Henken, S., Fitzpatrick, S., & Fitzpatrick, D. (2018). Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A rapid test for enteric coating thickness and integrity of controlled release pellet formulations. International Journal of Pharmaceutics, 544(1), 31-38. https://doi.org/10.1016/j.ijpharm.2018.04.018
There are no rapid dissolution based tests for determining coating thickness, integrity and drug concentration in controlled release pellets either during production or post-production. The manufacture of pellets requires several coating steps depend... Read More about Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A rapid test for enteric coating thickness and integrity of controlled release pellet formulations.