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Evaluation of a web-based intervention to optimize perinatal emotional wellbeing: A nested case-control study

Kuipers, Yvonne J; Bleijenbergh, Roxanne; Rimaux, Sophie; Mestdagh, Eveline


Roxanne Bleijenbergh

Sophie Rimaux

Eveline Mestdagh


Background/Objective: WazzUp Mama© is a remotely delivered web-based tailored intervention to prevent and reduce perinatal emotional distress, originally developed in the Netherlands. The current study aimed to evaluate the adapted WazzUp Mama© intervention in a Flemish (Dutch-speaking part of Belgium) perinatal population.

Methods: A 1:3 nested case-control study was performed. A data set including 676 participants (169 cases/507 controls) was composed based on core characteristics. Using independent t-test and chi-square, the two groups were compared for mean depression, self and perceived stigma, depression literacy scores, and for positive Whooley items and heightened depression scores. The primary analysis was adjusted for covariates.

Results: The number of positive Whooley items, the above cut-off depression scores, mean depression, perceived stigma, and depression literacy scores showed statistically significant differences between cases and controls, in favor of the intervention group. When adjusting for the covariates, the statistically significant differences between cases and controls remained for depression, perceived stigma, and depression literacy, for the positive Whooley items and for above cut-off depression scores.

Conclusion: WazzUp Mama© indicates to have a moderate to large positive effect on optimizing perinatal emotional wellbeing, to positively change perceived stigma and to increase depression literacy.

Journal Article Type Article
Acceptance Date Oct 31, 2023
Online Publication Date Nov 7, 2023
Publication Date 2024-01
Deposit Date Nov 7, 2023
Publicly Available Date Nov 10, 2023
Journal International Journal of Clinical and Health Psychology
Electronic ISSN 2174-0852
Publisher Asociación Española de Psicología Conductual
Peer Reviewed Peer Reviewed
Volume 24
Issue 1
Article Number 100422
Keywords Depression literacy; Digital intervention; Emotional wellbeing; Perinatal stigma
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