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Cochrane EPOC Protocol Providing medication adherence feedback to healthcare providers. The effect on care and outcomes. Protocol for a Cochrane review update Authors

Hassett, Richard; Sabatier, Brigitte; Savoldelli, Virginie; Mair, Alpana; Hanley, Janet; Dima, Alex; Paterson, Ruth


Brigitte Sabatier

Virginie Savoldelli

Alex Dima


This is a protocol for a Cochrane Review (update).

Key barriers to effectively supporting adherence include poor awareness amongst healthcare professionals (HCPs), scarce clinical tools and interventions, and suboptimal patient-provider communication. A Cochrane review assessed the impact of feedback interventions amongst physicians published until 2016. Other HCPs are increasingly involved in supporting adherence.

To assess the effects of providing healthcare providers with medication adherence feedback as a mechanism for improving patients’ medication adherence. To assess the impact of the intervention upon clinical outcomes, patient-reported outcomes, economic/financial outcomes and processes of care.

Search methods
We will search RCTs and cluster RCTs on CENTRAL, CINAHL, Embase, MEDLINE, PsychArticles and PsychInfo, and grey literature sources.

Selection criteria
Inclusion criteria are any reported intervention providing adherence feedback to HCPs as a key component, for long term medication for chronic diseases.

Data collection and analysis
One author performs title and abstract screening. Four authors will review full texts, extract data, and assess risk of bias. We will assess intervention effects on medication adherence, clinical outcomes, patient-reported outcomes, economic/financial outcomes and processes of care. We will assess heterogeneity, sensitivity, and undertake meta-analysis where appropriate.

Main results
The search yielded 4415 articles (pending grey literature). Publication is anticipated Q1 2023.

Author’s conclusions
Medication adherence feedback to HCPs could contribute significantly to reducing key barriers associated with poor adherence. The Cochrane review will provide evidence of effectiveness amongst HCPs whist updating that regarding physicians.

Working Paper Type Working Paper
Publication Date Aug 19, 2022
Deposit Date Sep 7, 2022
Publicly Available Date Sep 7, 2022
Public URL
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