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Priorities for future intensive care research in the UK: results of a James Lind Alliance Priority Setting

Reay, Hannah; Arulkumaran, Nishkantha; Brett, Stephen J; Clarke, Tessa; Plowright, Catherine; Peskett, Mo; Ramsay, Pam


Hannah Reay

Nishkantha Arulkumaran

Stephen J Brett

Tessa Clarke

Catherine Plowright

Mo Peskett

Pam Ramsay


This James Lind Alliance (JLA) Priority Setting Partnership aimed to identify and prioritise unanswered questions about
adult intensive care that are important to people who have been critically ill, their families, and the health professionals
who care for them. Consensus techniques (modified Delphi and Nominal Group) were used to generate suggestions using online and postal surveys. Following verification and iterative editorial review, research topics were constructed from these suggestions. These topics were presented in a second online and postal survey for rating. A Nominal Group of 21 clinicians, patients and family representatives subsequently met to rank the most important research topics and produce a prioritised list. The project was coordinated by a representative Steering Group and independently overseen by the JLA. The initial survey and review of the literature generated over 1,300 suggestions. Preliminary editing and verification permitted us to encapsulate these suggestions within 151 research topics. Iterative review by members of the Steering Group produced 37 topic statements, subsequently rated by participants. Using the mode to determine importance, 19 topics were presented to the group from which a ‘top three’ intensive care research priorities were identified and a
further nine topics were prioritised. By applying and adapting the JLA methodology to focus on an area of care rather than to a single disease, we have provided a means to ensure that patients, their families and professionals materially contribute to the prioritisation of intensive care research in the UK.


Reay, H., Arulkumaran, N., Brett, S. J., Clarke, T., Plowright, C., Peskett, M., & Ramsay, P. (2014). Partnership. Journal of the Intensive Care Society, 15, 288-296.

Journal Article Type Article
Acceptance Date Sep 9, 1999
Publication Date 2014-10
Deposit Date Jun 28, 2016
Print ISSN 1751-1437
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 15
Pages 288-296
Keywords Adult; consensus; intensive care; research; uncertainty;
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